Fig. 4From: Skeletal standardized uptake values obtained by quantitative SPECT/CT as an osteoblastic biomarker for the discrimination of active bone metastasis in prostate cancerChanges in analysis parameters with skeletal disease extent. There was significant change in alkaline phosphatase (ALP, a), prostate specific antigen (PSA, b), maximum and average of standardized uptake values (SUVmax, c; SUVave, d) with change in extent of disease (EOD) grade. ALP and PSA demonstrated an increasing trend with increase in EOD grade, while SUVmax showed a relatively lower maximum value in grade 4 disease. Please note that the scale of the graph for PSA (b) is logarithmicBack to article page