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Table 3 Attenuation correction techniques

From: PET/MRI: a frontier in era of complementary hybrid imaging

Technique

Merits

Demerits

References

Dixon (MRI)

Distinguishes fat from water

Localises uptake volume of PET

Extracts the lung with segmentation

Limited usage for attenuation correction

Needs different echo times

Cannot be used for detection of bone

(Martinez-Möller et al. 2009; Hu et al. 2009; Schulz et al. 2011)

UTE (MRI)

Aids in detection of bone region

Consumes extra time for MRI data acquisition

Not applicable for whole body imaging

(Schulz et al. 2011; Keereman et al. 2010; Catana et al. 2010)

Atlas &Template (MRI)

Faster process

Minimal or no dosage is required

Causes anatomical abnormalities

Not applicable for whole body imaging

Certain FOV gets truncated

Requires templates for coils

(Hofmann et al. 2008; Kops and Herzog 2013; Malone et al. 2011; Klein et al. 2010)

Emission (PET)

Minimal or zero additional acquisition time.

Uses TOF information also.

Less response to radionuclides such as FDG

Requires templates for coils

(Nuyts et al. 1999; Defrise et al. 2012; Rezaei et al. 2012; Boellaard et al. 2014)

Transmission (PET)

Primarily used for analysis of field of view

Needs additional dose of radionuclides

The attenuation map is corrupted with noise

The spatial resolution is minimal

(Berker et al. 2014; Mollet et al. 2012; Mollet et al. 2012; Mollet et al. 2014; Watson et al. 2013)