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Table 3 Diagnostic performances

From: A prospective study determining and comparing the diagnostic accuracy of fluoride-PET/CT, choline-PET/CT, whole-body bone SPECT/CT and whole-body MRI for the detection of bone metastases in patients with prostate cancer

 

NaF-PET/CT (n = 213)

Choline-PET/CT (n = 104)

WB-SPECT/CT (n = 109)

WB-MRI (n = 213)

True positive results

59 (28)

30 (29)

31 (28)

55 (26)

False positive results

11 (5)

1 (1)

7 (6)

15 (7)

True negative results

140 (66)

72 (69)

71 (65)

136 (64)

False negative results

3 (1)

1 (1)

0 (0)

7 (3)

Sensitivity (%)

95 (95%CI:87–99)

97 (95%CI:83–100)

100 (95%CI:89–100)

89 (95%CI:78–95)

Specificity (%)

93 (95%CI:87–96)

99 (95%CI:93–100)

91 (95%CI:82–96)

90 (95%CI:84–94)

Positive predicative value (%)

84 (95%CI:74–92)

97 (95%CI:83–100)

82 (95%CI:66–92)

79 (95%CI:67–87)

Negative predicative value (%)

98 (95%CI:94–100)

99 (95%CI:93–100)

100 (95%CI:95–100)

95 (95%CI:90–98)

Overall accuracy (%)

93 (95%CI:89–96)

98 (95%CI:93–100)

94 (95%CI:87–97)

90 (95%CI:85–93)

  1. Unless otherwise indicated, data are numbers of patients, with percentages in parenthesis
  2. 95%CI 95% confidence interval