Skip to main content

Table 4 Comparison of diagnostic performances - Patients naïve to ADT vs patients receiving ADT

From: A prospective study determining and comparing the diagnostic accuracy of fluoride-PET/CT, choline-PET/CT, whole-body bone SPECT/CT and whole-body MRI for the detection of bone metastases in patients with prostate cancer

 

N

Patients naïve to ADT

N

Patients receiving ADT

NaF-PET/CT

Sensitivity

78

86 (95%CI:42–100)

132

98 (95%CI:90–100)

Specificity

97 (95%CI:90–100)

88 (95%CI:79–95)

Overall accuracy

96 (95%CI: 89–99)

92 (95%CI: 87–96)

Choline-PET/CT

Sensitivity

39

100 (95%CI:29–100)

64

96 (95%CI:81–100)

Specificity

97 (95%CI:85–100)

100 (95%CI:91–100)

Overall accuracy

97 (95%CI: 87–100)

98 (95%CI: 92–100)

WB-SPECT/CT

Sensitivity

39

100 (95%CI:40–100)

68

100 (95%CI:87–100)

Specificity

94 (95%CI:81–99)

88 (95%CI:74–96)

Overall accuracy

95 (95%CI: 83–100)

93 (95%CI: 84–98)

WB-MRI

Sensitivity

78

100 (95%CI:59–100)

132

89 (95%CI:77–96)

Specificity

90 (95%CI:81–96)

90 (95%CI:81–95)

Overall accuracy

91 (95%CI: 82–96)

89 (95%CI: 83–94)

  1. ADT androgen deprivation therapy, N number of patients, 95%CI 95% confidence interval