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Table 2 Main correlations between PET/CT parameters and functional or exercise-related parameters

From: Assessment of 18F-FDG uptake in idiopathic pulmonary fibrosis: influence of lung density changes

Pearson correlation tests SUVmean-uncorr SUVmean-corr SUVmax-uncorr SUVmax-corr CTmean (HU)
PFT VC (%) r −0.447 − 0.065 − 0.408 −0.082 − 0.518
p 0.013* 0.733 0.025* 0.666 0.003*
FVC (%) r −0.505 −0.08 −0.413 − 0.072 −0.57
p 0.004* 0.667 0.021* 0.7 0.001*
TLC (%) r −0.568 −0.165 −0.527 − 0.003 −0.595
p 0.001* 0.382 0.003* 0.987 0.001*
DLCO (ml/ min/mmHg) r −0.247 −0.398 −0.056 − 0.268 0.013
p 0.18 0.026* 0.764 0.145 0.945
6MWT SaO2 post-exercise r −0.344 −0.376 −0.064 − 0.062 −0.18
p 0.073 0.049* 0.746 0.755 0.36
Δ SaO2 (between the pre- and post-exercise) r 0.366 0.401 0.056 0.172 0.174
p 0.055 0.034* 0.777 0.38 0.375
Δ SaO2 post-exercise (between the test at the time of PET and the test at 1 year) r 0.38 0.527 0.017 0.261 0.074
p 0.12 0.024* 0.947 0.296 0.769
Distance traveled r 0.037 −0.217 0.354 0.032 0.199
p 0.85 0.266 0.064 0.87 0.311
  SUV mean-uncorr r      0.755
p      < 0.001*
  SUV mean-corr r      −0.091
p      0.627
  1. Data presented were obtained using Pearson correlation tests with significant correlations highlighted in bold (corresponding to p values < 0.05). The r corresponds to the correlation coefficient. PFT = pulmonary function tests
  2. CV vital capacity, FVC Forced vital capacity, TLC Total lung capacity, DLCO carbon monoxide diffusion, 6MWT 6-min walking test, SaO2 oxygen saturation, SUV standardized uptake value