Assessment of 18F-FDG uptake in idiopathic pulmonary fibrosis: influence of lung density changes

European Journal of Hybrid Imaging

EJNMMI Multimodality Journal

Table 2 Main correlations between PET/CT parameters and functional or exercise-related parameters

Pearson correlation tests			SUVmean-uncorr	SUVmean-corr	SUVmax-uncorr	SUVmax-corr	CTmean (HU)
PFT	VC (%)	r	−0.447	− 0.065	− 0.408	−0.082	− 0.518
	VC (%)	p	0.013*	0.733	0.025*	0.666	0.003*
	FVC (%)	r	−0.505	−0.08	−0.413	− 0.072	−0.57
	FVC (%)	p	0.004*	0.667	0.021*	0.7	0.001*
	TLC (%)	r	−0.568	−0.165	−0.527	− 0.003	−0.595
	TLC (%)	p	0.001*	0.382	0.003*	0.987	0.001*
	DLCO (ml/ min/mmHg)	r	−0.247	−0.398	−0.056	− 0.268	0.013
	DLCO (ml/ min/mmHg)	p	0.18	0.026*	0.764	0.145	0.945
6MWT	SaO₂ post-exercise	r	−0.344	−0.376	−0.064	− 0.062	−0.18
	SaO₂ post-exercise	p	0.073	0.049*	0.746	0.755	0.36
	Δ SaO₂ (between the pre- and post-exercise)	r	0.366	0.401	0.056	0.172	0.174
	Δ SaO₂ (between the pre- and post-exercise)	p	0.055	0.034*	0.777	0.38	0.375
	Δ SaO₂ post-exercise (between the test at the time of PET and the test at 1 year)	r	0.38	0.527	0.017	0.261	0.074
		p	0.12	0.024*	0.947	0.296	0.769
	Distance traveled	r	0.037	−0.217	0.354	0.032	0.199
	Distance traveled	p	0.85	0.266	0.064	0.87	0.311
	SUV mean-uncorr	r					0.755
	SUV mean-uncorr	p					< 0.001*
	SUV mean-corr	r					−0.091
	SUV mean-corr	p					0.627

Data presented were obtained using Pearson correlation tests with significant correlations highlighted in bold (corresponding to p values < 0.05). The r corresponds to the correlation coefficient. PFT = pulmonary function tests
CV vital capacity, FVC Forced vital capacity, TLC Total lung capacity, DLCO carbon monoxide diffusion, 6MWT 6-min walking test, SaO₂ oxygen saturation, SUV standardized uptake value