Fig. 67

¹⁸F-FMISO, characterisation of a brain lesion and comparison to ¹¹C-methionine. Clinical history: 15 y.o. boy. High-grade glioblastoma, sub-totally removed and treated with radiotherapy. MRI: persistence of expansive lesion in thalamic area (a). PET/CT findings: ¹¹C-methionine shows peripheral uptake in the right thalamus tumour, probably related to residual viable tumour or relapse despite its low intensity (b). ¹⁸F-FMISO PET/CT showed hypoxic area in previously methionine uptake described lesion (c), suggesting a relapse