Fig. 71

18F-NaF, breast cancer restaging. Clinical history: 72 y.o. woman with history of breast cancer (infiltrating ductal carcinoma, ER+, PR, and HER2 neg). Diffuse bone pain, no evidence of bone metastases on bone scintigraphy (a anterior view). PET/CT findings: highly heterogeneous uptake in the cranium, spine, pelvic grid and femurs, consistent with bone marrow involvement (b MIP). MRI confirms multiple small sized lesions (c)