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EJNMMI Reports
Fig. 5 | European Journal of Hybrid Imaging

Fig. 5

From: 18F-fluorothymidine (FLT)-PET and diffusion-weighted MRI for early response evaluation in patients with small cell lung cancer: a pilot study

Fig. 5

N-site (12-N1): FDG-PET (axial (a), coronal (b), sagittal (c)), FLT-PET (axial (d), coronal (e), sagittal (f)), and DW-MRI (transversal (g), coronal (h), sagittal (i)), and voxel-by-voxel scatterplot of FDG-SUV vs. FLT-SUV (j), and FLT-SUV vs. ADC (k). This N-site were clearly detectable on FDG-PET (SUVpeak 11.6), FLT-uptake was the highest of all N-sites (SUVpeak 2.4), and detectable on DW-MRI (ADCmedian 1.56 × 10−3 mm2/s). The most aggressive regions (MTV70, PTV70, and DWTV50) were located centrally within the tumor on all imaging modalities, and voxel-by-voxel correlations were moderate for FDG-SUV vs. FLT-SUV (r = 0.55) (j) and for FLT-SUV vs. ADC (r = − 0.44) (k). This N-site progressed during chemotherapy

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