EJNMMI Reports

Table 4 Overall diagnostic accuracy using standardized reporting criteria (Deauville, Hopkins, and Cuneo scores)

From: Does a 6-point scale approach to post-treatment 18F-FDG PET-CT allow to improve response assessment in head and neck squamous cell carcinoma? A multicenter study

Hopkins score (HS)	Tref	Nref	TNref
1, 2, 3: absent disease
4, 5: persistent disease
Characteristic
Sensitivity	39.3	10.7	50.0
Specificity	75.8	96.7	73.6
NPV	80.2	77.9	82.7
PPV	33.3	50.0	36.8
Overall accuracy	67.2	76.5	68.1
Cuneo score (CS # 1)	Tref	Nref	TNref
1, 2, 3, 4: absent disease
5, 6: persistent disease
Characteristic
Sensitivity	10.7	35.7	14.3
Specificity	95.6	100	95.6
NPV	77.7	77.1	78.4
PPV	42.9	100	50.0
Overall accuracy	75.6	77.5	76.5
Cuneo score (CS # 2)	Tref	Nref	TNref
1, 2, 3: absent disease
4, 5, 6: persistent disease
Characteristic
Sensitivity	39.3	10.7	50
Specificity	75.8	96.7	73.6
NPV	80.2	77.9	82.7
PPV	33.3	50	36.8
Overall accuracy	67.2	76.5	68.1
Cuneo score (CS # 3)	Tref	Nref	TNref
1, 2: absent disease
3, 4, 5, 6: persistent disease
Characteristic
Sensitivity	53.6	17.9	57.1
Specificity	64.8	94.5	62.6
NPV	81.9	78.9	82.6
PPV	31.9	50	32
Overall accuracy	62.2	76.5	61.3
Deauville score (DS # 1)	Tref	Nref	TNref
1, 2, 3: absent disease
4, 5: persistent disease
Characteristic
Sensitivity	39.3	10.7	50.0
Specificity	75.8	96.7	73.6
NPV	80.2	77.9	82.7
PPV	33.3	50.0	36.8
Overall accuracy	67.2	76.5	68.1
Deauville score (DS # 2)	Tref	Nref	TNref
1, 2: absent disease
3, 4, 5: persistent disease
Characteristic
Sensitivity	64.3	17.9	67.9
Specificity	54.9	85.7	50.5
NPV	83.3	77.2	83.6
PPV	30.5	27.8	29.7
Overall accuracy	57.1	69.7	54.6

NPV negative predictive value, PPV positive predictive value

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