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Table 2 Primary tumor semiquantitative PET parameters and p16 status data for the 28 patients with newly diagnosed oropharyngeal squamous cell carcinoma

From: Texture indices of 4′-[methyl-11C]-thiothymidine uptake predict p16 status in patients with newly diagnosed oropharyngeal squamous cell carcinoma: comparison with 18F-FDG uptake

PET parameter p16 positive (n = 13) p16 negative (n = 15) P value
Mean SD Mean SD
11C-4DST
 SUVmax 7.79 1.48 9.10 2.64 0.066
 Homogeneity 0.360 0.360 0.330 0.090 0.012
 Entropy 2.078 0.177 2.058 0.273 0.857
 SRE 0.942 0.014 0.950 0.037 0.005
 LRE 1.272 0.077 1.241 0.240 0.009
 LGZE 0.00634 0.00210 0.00499 0.00265 0.053
 HGZE 241.08 101.89 346.99 172.82 0.042
18F-FDG
 SUVmax 15.29 6.09 18.08 9.68 0.684
 Homogeneity 0.253 0.062 0.305 0.177 0.822
 Entropy 2.147 0.261 1.920 0.538 0.255
 SRE 0.963 0.023 0.930 0.108 0.822
 LRE 1.183 0.180 1.665 1.419 0.857
 LGZE 0.00263 0.00177 0.00193 0.00131 0.619
 HGZE 970.54 640.41 1134.29 799.85 0.651
  1. SUVmax maximum standardized uptake value, SRE short-run emphasis, LRE long-run emphasis, LGZE low gray-level zone emphasis, HGZE high gray-level zone emphasis