Fig. 5
From: Combined amino acid PET-MRI for identifying recurrence in post-treatment gliomas: together we grow
Concordant PET, perfusion, diffusion and enhancement in a case of recurrence: 40-year-old male diagnosed with anaplastic ODG 15 months back. Underwent surgical excision followed by radiotherapy completed 13 months earlier. PET image overlaid over T1 MPRAGE (A) shows a large area of uptake in the left temporoparietal region (white arrow). rCBV map (B) generated with the leakage correction algorithm shows elevated perfusion in the same region (white arrow) with diffusion restriction on the ADC map (white arrow in C). Note enhancement on the post-contrast image (white arrow in D). In view of unequivocal evidence of recurrence, surgery was planned. Post-contrast axial CT brain acquired prior to surgery (E) shows an enhancing left parietal lesion (white arrow). Post-operative plain axial CT brain (F) shows the resection cavity (white arrow) with gross total excision. Histopathology revealed recurrent GBM. This is a case of recurrence where the PET, perfusion, diffusion, and contrast images were concordant with good spatial congruence