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Table 3 Diagnostic performance of CT-MPI on a per patient and per-territory analysis using 82Rb PET-MPI as the reference standard

From: Static CT myocardial perfusion imaging: image quality, artifacts including distribution and diagnostic performance compared to 82Rb PET

  Per-patient Per-territory    
  LAD LCx RCA All-territories  
Sensitivity 88.9% [65.3–98.6] 91.7% 80% 44.4% 73.1% [52.2–88.4]
Specificity 57.7% [36.9–76.7] 56.3% 74.4% 62.9% 65.1% [53.4–74.6]
Positive likelihood ratio 2.1 [1.3–3.4] 2.10 3.12 1.23 2.15 [1.5–3.1]
Negative likelihood ratio 0.19 [0.1–0.7] 0.15 0.27 0.88 0.41 [0.2–0.8]
Positive predictive value 59.26% [38.8–77.6] 44% 28.57% 23.53% 33.93% [21.8–47.8]
Negative predictive value 88.2% [63.6–98.5] 94.7% 96.77% 81.48% 90.79% [82.6–96.4]
Accuracy 70.5% 65.6% 75.0% 59.1% 67.7%
Area under the ROC curve 0.73 [0.57–0.85] 0.74 0.77 0.54 0.69[0.60–0.77]
  1. CT-MPI computed tomography myocardial perfusion imaging; 82Rb PET MPI Rubidium-positron emission tomography myocardial perfusion imaging; LAD left descending coronary artery; LCx left circumflex coronary artery; RCA right coronary artery; ROC receive operating characteristic curve