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Table 3 Diagnostic performance of CT-MPI on a per patient and per-territory analysis using 82Rb PET-MPI as the reference standard

From: Static CT myocardial perfusion imaging: image quality, artifacts including distribution and diagnostic performance compared to 82Rb PET

 

Per-patient

Per-territory

   
 

LAD

LCx

RCA

All-territories

 

Sensitivity

88.9% [65.3–98.6]

91.7%

80%

44.4%

73.1% [52.2–88.4]

Specificity

57.7% [36.9–76.7]

56.3%

74.4%

62.9%

65.1% [53.4–74.6]

Positive likelihood ratio

2.1 [1.3–3.4]

2.10

3.12

1.23

2.15 [1.5–3.1]

Negative likelihood ratio

0.19 [0.1–0.7]

0.15

0.27

0.88

0.41 [0.2–0.8]

Positive predictive value

59.26% [38.8–77.6]

44%

28.57%

23.53%

33.93% [21.8–47.8]

Negative predictive value

88.2% [63.6–98.5]

94.7%

96.77%

81.48%

90.79% [82.6–96.4]

Accuracy

70.5%

65.6%

75.0%

59.1%

67.7%

Area under the ROC curve

0.73 [0.57–0.85]

0.74

0.77

0.54

0.69[0.60–0.77]

  1. CT-MPI computed tomography myocardial perfusion imaging; 82Rb PET MPI Rubidium-positron emission tomography myocardial perfusion imaging; LAD left descending coronary artery; LCx left circumflex coronary artery; RCA right coronary artery; ROC receive operating characteristic curve