Volumetric parameters of the primary tumor and whole-body tumor burden derived from baseline 18F-FDG PET/CT can predict overall survival in non-small cell lung cancer patients: initial results from a single institution

EJNMMI Reports

Table 2 ROC analysis, AUC, and Optimal Cutoff Value of Each Metabolic Parameter

	AUC	P value	95% CI		Cut off point	Sensitivity (%)	Specificity (%)
	AUC	P value	Lower	Upper	Cut off point	Sensitivity (%)	Specificity (%)
Primary SUV_max	.688	0.130	.485	.890	> 11.30	75.0	52.6
Primary SUV_peak	.845	0.063	.538	.923	> 9.55	74.0	68.4
Primary SUV_mean	.849	0.071	.523	.924	> 8.05	62.5	84.2
Tu MTV	.730	0.005*	.687	1.000	> 30.9	87.5	73.7
Tu TLG	.724	0.005*	.704	.993	> 190.0	87.5	61.2
WB MTV	.757	0.038*	.572	.941	> 141.98	87.5	57.9
WB TLG	.783	0.022*	.605	.961	> 832.4	87.5	63.2

ROC Receiver operating characteristic curve, AUC Area under the curve, CI Confidence interval, MTV Metabolic tumor volume, TLG Total lesion glycolysis, WB MTV Whole-body metabolic tumor volume, WB TLG Whole-body total lesion glycolysis,
Bold are highlighted the p values that reached statistical significance is P value < 0.05