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  1. Positron emission tomography (PET) imaging with amyloid-beta (Aβ) tracers and 2-[18F] fluoro-2-Deoxy-d-glucose (18F-FDG) is extensively employed in Alzheimer’s disease (AD) studies as biomarkers of AD pathology a...

    Authors: Alison Myoraku, Gregory Klein, Susan Landau and Duygu Tosun

    Citation: European Journal of Hybrid Imaging 2022 6:2

    Content type: Original article

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  2. Rubidium-82 positron emission tomography (82Rb PET) MPI is considered a noninvasive reference standard for the assessment of myocardial perfusion in coronary artery disease (CAD) patients. Our main goal was to co...

    Authors: João R. Inácio, Sriraag Balaji Srinivasan, Terrence D. Ruddy, Robert A. deKemp, Frank Rybicki, Rob S. Beanlands, Benjamin J. W. Chow and Girish Dwivedi

    Citation: European Journal of Hybrid Imaging 2022 6:1

    Content type: Original article

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  3. The positron emission tomography (PET) radioligand 18F-THK5351 is now used to evaluate monoamine oxidase B expression in the reactive astrogliosis seen in various central nervous diseases. Traumatic brain injury ...

    Authors: Tetsuhiro Hatakeyama, Kenya Kawakita, Nobuyuki Kawai, Hajime Shishido, Yuka Yamamoto, Yoshihiro Nishiyama and Keisuke Miyake

    Citation: European Journal of Hybrid Imaging 2021 5:26

    Content type: Case report

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  4. Pulmonary embolism is indicated by ventilation/perfusion (V/P) mismatches in ventilation/perfusion scintigraphy. However, other pathologies may also evoke segmental or lobar mismatches. Thus, diagnosis can be ...

    Authors: David Kersting, Christoph Rischpler, Till Plönes, Clemens Aigner, Lale Umutlu, Ken Herrmann and Hubertus Hautzel

    Citation: European Journal of Hybrid Imaging 2021 5:25

    Content type: Case report

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  5. To evaluate the diagnostic and prognostic significance of combined cardiac 18F-fluorodeoxyglucose (FDG) PET/MRI with T1/T2 mapping in the evaluation of suspected cardiac sarcoidosis.

    Authors: Edward Cheung, Sarah Ahmad, Matthew Aitken, Rosanna Chan, Robert M. Iwanochko, Meyer Balter, Ur Metser, Patrick Veit-Haibach, Filio Billia, Yasbanoo Moayedi, Heather J. Ross and Kate Hanneman

    Citation: European Journal of Hybrid Imaging 2021 5:24

    Content type: Original article

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  6. 18F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging (18F-FDG PET/MRI) may improve cancer staging by combining sensitive cancer detection with high-contrast resolution and detail. We co....

    Authors: Amy R. Sharkey, Bert-Ram Sah, Samuel J. Withey, Shaheel Bhuva, Radhouene Neji, Sami Jeljeli, Adrian Green, Gary J. R. Cook and Vicky Goh

    Citation: European Journal of Hybrid Imaging 2021 5:23

    Content type: Original article

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  7. Early [68Ga]Ga-DOTA-TOC PET/CT imaging after peptide receptor radionuclide therapy (PRRT) in neuroendocrine neoplasm patients is often used as a prognosticator for survival, but lacks validity. This study investi...

    Authors: Sander C. Ebbers, Muriël Heimgartner, Maarten W. Barentsz, Rachel S. van Leeuwaarde, Mark J. C. van Treijen, Marnix M. E. G. Lam and Arthur J. A. T. Braat

    Citation: European Journal of Hybrid Imaging 2021 5:22

    Content type: Original article

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  8. Positron emission tomography (PET) using O-(2-[18F]fluoroethyl)-L-tyrosine (18F-FET) PET has been shown to be a useful tool for differentiating radiation therapy outcomes, such as brain metastasis recurrence or r...

    Authors: Samirah Alshehri, John Prior, Mohammed Moshebah, Luis Schiappacasse and Vincent Dunet

    Citation: European Journal of Hybrid Imaging 2021 5:21

    Content type: Case report

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  9. This study was addressed to evaluate the temporal and spatial changes in regional cerebral blood flow (rCBF) of patients with neuropsychiatric systemic lupus erythematosus (NPSLE). Our objective was to correla...

    Authors: Ana Carolina Trevisan, Leonardo Alexandre-Santos, Rodrigo Luppino Assad, Emerson Nobuyuki Itikawa, Felipe Arriva Pitella, Mery Kato, José Henrique Silvah, Antonio Carlos Santos, Paulo Louzada-Junior and Lauro Wichert-Ana

    Citation: European Journal of Hybrid Imaging 2021 5:19

    Content type: Original article

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  10. Giant cell arteritis (GCA) is an inflammation of large and medium sized vessels, mainly affecting people over 50 years of age. Diagnosis needs to be made quickly to prevent complications. Steroids treatment sh...

    Authors: Tamer Anati and Michal Hoffman Ben Shabat

    Citation: European Journal of Hybrid Imaging 2021 5:20

    Content type: Case report

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  11. A 73-year-old man with a history of marginal zone lymphoma was admitted to the emergency room for diplopia and ipsilateral headache. The Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tom...

    Authors: C. Van Bogaert, C. Mathey, I. Vierasu, N. Trotta, L. Rocq, A. Wolfromm, V. De Wilde and S. Goldman

    Citation: European Journal of Hybrid Imaging 2021 5:18

    Content type: Case report

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  12. We report a rare case of chylothorax with lymphocele formation post esophageal duplication cyst (EDC) excision in a 2 year old male child. Patient developed chylothorax after excision of EDC. Pleural fluid cyt...

    Authors: Naveen Yadav, Sameer Taywade, Rajesh Kumar, Arun Prashanth and Rahul Saxena

    Citation: European Journal of Hybrid Imaging 2021 5:17

    Content type: Case report

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  13. The use of 18F-FDG Positron emission tomography/Computed tomography (PET/CT) in the initial staging of many cancers is clearly established. Most soft tissue sarcoma (STS) has a high affinity for 18F-FDG, which is...

    Authors: Rafael Hernando Reyes Marlés, José Luis Navarro Fernández, José Pablo Puertas García-Sandoval, Fernando Santonja Medina, Laroussi Mohamed Salem, Laura Frutos Esteban, José Fulgencio Contreras Gutiérrez, María Isabel Castellón Sánchez, Guadalupe Ruiz Merino and María Antonia Claver Valderas

    Citation: European Journal of Hybrid Imaging 2021 5:16

    Content type: Original article

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  14. The aim of this study is to compare the diagnostic accuracy of amino acid PET, MR perfusion and diffusion as stand-alone modalities and in combination in identifying recurrence in post-treatment gliomas and to...

    Authors: Shumyla Jabeen, Arpana Arbind, Dinesh Kumar, Pardeep Kumar Singh, Jitender Saini, Nishanth Sadashiva, Uday Krishna, Arivazhagan Arimappamagan, Vani Santosh and Chandana Nagaraj

    Citation: European Journal of Hybrid Imaging 2021 5:15

    Content type: Original article

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  15. Artificial intelligence (AI) technology has been increasingly developed and studied in cardiac imaging. This systematic review summarizes the latest progress of image segmentation, quantification, and the clin...

    Authors: Lu Zhang, Jianqing Sun, Beibei Jiang, Lingyun Wang, Yaping Zhang and Xueqian Xie

    Citation: European Journal of Hybrid Imaging 2021 5:14

    Content type: Review

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  16. Use of 11C-Choline PET/CT is gaining ground in detecting hyperfunctioning parathyroid glands in primary hyperparathyroidism. The purpose of this study was to evaluate the robustness of 11C-Choline PET/CT by asses...

    Authors: Julie Wulf Christensen, Lars Thorbjørn Jensen, Susanne Bonnichsen Søndergaard, Rikke Broholm, Christian Haarmark, Martin Krakauer, Finn Noe Bennedbæk, Bo Zerahn, Waldemar Trolle, Christoffer Holst Hahn and Bent Kristensen

    Citation: European Journal of Hybrid Imaging 2021 5:13

    Content type: Original article

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  17. 68Ga-fibroblast activation protein-specific enzyme inhibitor 04 (FAPI-04) is a radiolabelled molecular agent targeting the inhibitor of fibroblast activation protein (FAP), which is often present in tumor stroma....

    Authors: Yi Shou, Qiaoyi Xue, Jianmin Yuan and Jun Zhao

    Citation: European Journal of Hybrid Imaging 2021 5:12

    Content type: Case report

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  18. Gallium 68-tetraazacyclododecane-tetraacetic acid-octreotate ([68Ga]Ga-DOTA-TATE) is a selective somatostatin analogue ligand, which shows increased affinity for somatostatin receptor subtype (SSTR) 2 and has ...

    Authors: Fuad Novruzov, Aziz Aliyev, Ming Young S. Wan, Rizwan Syed, Elnur Mehdi, Irada Aliyeva, Francesco Giammarile, Jamshed B. Bomanji and Irfan Kayani

    Citation: European Journal of Hybrid Imaging 2021 5:10

    Content type: Original article

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  19. Pancreatic neuroendocrine tumor (PNET) is a subgroup of neuroendocrine tumor (NET) that has unique biology and natural history. The histological classification has a major role in the management of this pathol...

    Authors: Marcello Moro Queiroz, Carlos Diego Holanda Lopes, Alessandra Corte Real Salgues, Felipe de Galiza Barbosa, Emerson Shigueaki Abe, Thales Parenti Silveira, Marcel Cerqueira Cesar Machado and Fernanda Cunha Capareli

    Citation: European Journal of Hybrid Imaging 2021 5:9

    Content type: Case report

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  20. SMARCA4-deficient thoracic tumor (SMARCA4-DTT) is a distinct entity of undifferentiated thoracic malignancies newly introduced in 2015. Due to its unique clinical characteristic with aggressive thoracic tumor ...

    Authors: Tsubasa Okazaki, Kota Yokoyama, Jyunichi Tsuchiya, Takayuki Honda, Yuya Ishikawa, Susumu Kirimura, Yasunari Miyazaki and Ukihide Tateishi

    Citation: European Journal of Hybrid Imaging 2021 5:8

    Content type: Case report

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  21. Patients with metastatic cancer to the brain have a poor prognosis. In clinical practice, MRI is used to delineate, diagnose and plan treatment of brain metastases. However, MRI alone is limited in detecting m...

    Authors: Knut Johannessen, Erik Magnus Berntsen, Håkon Johansen, Tora S. Solheim, Anna Karlberg and Live Eikenes

    Citation: European Journal of Hybrid Imaging 2021 5:7

    Content type: Case report

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  22. Multiple myeloma is characterized by malignant proliferation of clonal plasma cells. Usually, appears as a generalized disease but it can present as solitary bone plasmacytoma or a solitary soft tissue mass or...

    Authors: Alejandro Martí, Sarai Morón, Sandra Chinchilla and Eliana González

    Citation: European Journal of Hybrid Imaging 2021 5:6

    Content type: Case report

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  23. Respiratory motion during PET imaging reduces image quality. Data-driven gating (DDG) based on principal component analysis (PCA) can be used to identify respiratory signals. The use of DDG, without need for e...

    Authors: Sofia Kvernby, Nafsika Korsavidou Hult, Elin Lindström, Jonathan Sigfridsson, Gustav Linder, Jakob Hedberg, Håkan Ahlström, Tomas Bjerner and Mark Lubberink

    Citation: European Journal of Hybrid Imaging 2021 5:5

    Content type: Original article

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  24. Metabolic syndrome and its individual components lead to wide-ranging consequences, many of which affect the central nervous system. In this study, we compared the [18F]FDG regional brain metabolic pattern of par...

    Authors: Z. Képes, Cs. Aranyi, A. Forgács, F. Nagy, K. Kukuts, Zs. Hascsi, R. Esze, S. Somodi, M. Káplár, J. Varga, M. Emri and I. Garai

    Citation: European Journal of Hybrid Imaging 2021 5:3

    Content type: Original article

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  25. [18F]Fluoro-deoxy-glucose positron emission tomography/computed tomography (FDG-PET/CT) is used for response assessment during therapy in Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL). Clinicians report th...

    Authors: Charlotte Hornnes, Annika Loft, Liselotte Højgaard and Flemming Littrup Andersen

    Citation: European Journal of Hybrid Imaging 2021 5:2

    Content type: Original article

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  26. Dementia with Lewy bodies (DLB) is a common cause of dementia, but atrophy is mild compared to Alzheimer’s disease. We propose that DLB is associated instead with severe synaptic loss, and we test this hypothe...

    Authors: Nicolas Nicastro, Negin Holland, George Savulich, Stephen F. Carter, Elijah Mak, Young T. Hong, Selena Milicevic Sephton, Tim D. Fryer, Franklin I. Aigbirhio, James B. Rowe and John T. O’Brien

    Citation: European Journal of Hybrid Imaging 2020 4:25

    Content type: Case report

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  27. Bottom-of-sulcus dysplasia (BOSD) is a type of focal cortical dysplasia and an important cause of intractable epilepsy. While the MRI features of BOSD have been well documented, the contribution of PET to the ...

    Authors: S. U. Berlangieri, R. Mito, M. Semmelroch, M. Pedersen and G. Jackson

    Citation: European Journal of Hybrid Imaging 2020 4:23

    Content type: Short communication

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  28. Artificial intelligence (AI) refers to a field of computer science aimed to perform tasks typically requiring human intelligence. Currently, AI is recognized in the broader technology radar within the five key...

    Authors: Martina Sollini, Francesco Bartoli, Andrea Marciano, Roberta Zanca, Riemer H. J. A. Slart and Paola A. Erba

    Citation: European Journal of Hybrid Imaging 2020 4:24

    Content type: Review

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  29. 18F-fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) is used in the clinical management of oncologic and inflammatory pathologies. It may have utility in detecting radiotherapy (R....

    Authors: Alaa Mouminah, Austin J. Borja, Emily C. Hancin, Yu Cheng Chang, Thomas J. Werner, Samuel Swisher-McClure, Jonathan Korostoff, Abass Alavi and Mona-Elisabeth Revheim

    Citation: European Journal of Hybrid Imaging 2020 4:22

    Content type: Original article

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  30. In oropharyngeal squamous cell carcinoma (OPSCC), human papillomavirus (HPV)/p16 status is important as a prognostic biomarker.

    Authors: Ayumi Ihara-Nishishita, Takashi Norikane, Katsuya Mitamura, Yuka Yamamoto, Kengo Fujimoto, Yasukage Takami, Emi Ibuki, Nobuyuki Kudomi, Hiroshi Hoshikawa, Jun Toyohara and Yoshihiro Nishiyama

    Citation: European Journal of Hybrid Imaging 2020 4:20

    Content type: Original article

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  31. Coronavirus disease-19 (COVID-19) is only one of the many possible infectious and non-infectious diseases that may occur with similar imaging features in patients undergoing [18F]-fluorodeoxyglucose (18FDG) monit...

    Authors: Annalisa Papa, Chiara Pozzessere, Francesco Cicone, Fabiola Rizzuto and Giuseppe Lucio Cascini

    Citation: European Journal of Hybrid Imaging 2020 4:19

    Content type: Short communication

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  32. Novel reconstruction algorithms, such as xSPECT Bone, are gaining more and more importance in Nuclear Medicine. With xSPECT Bone, the reconstructed emission image is enhanced by the information obtained in the...

    Authors: Thiago V. M. Lima, Ujwal Bhure, Maria de Sol Pérez Lago, Yannick Thali, Savo Matijasevic, Justus Roos and Klaus Strobel

    Citation: European Journal of Hybrid Imaging 2020 4:18

    Content type: Case report

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  33. Prostate-specific membrane antigen positron emission tomography (PSMA-PET) has shown promise for detecting nodal and distant prostate cancer (PCa) metastases. However, its performance for local tumor staging i...

    Authors: Sungmin Woo, Soleen Ghafoor, Anton S. Becker, Sangwon Han, Andreas G. Wibmer, Hedvig Hricak, Irene A. Burger, Heiko Schöder and Hebert Alberto Vargas

    Citation: European Journal of Hybrid Imaging 2020 4:16

    Content type: Original article

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  34. This study prospectively assessed the diagnostic capacity of dynamic carbon-11 methionine (C-11 MET) positron-emission tomography (PET)/computed tomography for the diagnosis of pathologies in patients with pri...

    Authors: Takayoshi Shinya, Yoichi Otomi, Toshihiko Nishisho, Bettina Beuthien-Baumann, Michiko Kubo, Hideki Otsuka, Yoshimi Bando, Hiroaki Yanagawa, Koichi Sairyo and Masafumi Harada

    Citation: European Journal of Hybrid Imaging 2020 4:15

    Content type: Original article

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  35. Muscle enzymes are the major noninvasive diagnostic parameters useful in polymyositis/dermatomyositis (PM/DM). Few studies have yet correlated findings on 18F-FDG PET with disease activity in patients with PM/DM.

    Authors: Hanae Arai-Okuda, Takashi Norikane, Yuka Yamamoto, Katsuya Mitamura, Kengo Fujimoto, Yasukage Takami, Risa Wakiya, Shusaku Nakashima, Hiroaki Dobashi and Yoshihiro Nishiyama

    Citation: European Journal of Hybrid Imaging 2020 4:14

    Content type: Original article

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  36. Preclinical imaging is still seen as a new field, and its recognition as a specific topic occurring only about 20 years ago. Nuclear medicine technologists (NMTs) and radiographers’ skills covering technical, ...

    Authors: J.-P. Dillenseger, P. Choquet, E. R. Snay and P. Fragoso Costa

    Citation: European Journal of Hybrid Imaging 2020 4:12

    Content type: Review

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  37. The use of hybrid systems is increasingly growing in Europe and this is progressively important for the final result of diagnostic tests. As an integral part of the hybrid imaging system, computed tomography (...

    Authors: Luca Camoni, Andrea Santos, Marieclaire Attard, Marius Ovidiu Mada, Agata Karolina Pietrzak, Sonja Rac, Sebastijan Rep, Christelle Terwinghe and Pedro Fragoso Costa

    Citation: European Journal of Hybrid Imaging 2020 4:11

    Content type: Review

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  38. Hybrid PET/MRI can non-invasively improve localization and delineation of the epileptic focus (EF) prior to surgical resection in medically refractory epilepsy (MRE), especially when MRI is negative or equivoc...

    Authors: Stefan E. Poirier, Benjamin Y. M. Kwan, Michael T. Jurkiewicz, Lina Samargandy, David A. Steven, Ana Suller-Marti, Victor Lam Shin Cheung, Ali R. Khan, Jonathan Romsa, Frank S. Prato, Jorge G. Burneo, Jonathan D. Thiessen and Udunna C. Anazodo

    Citation: European Journal of Hybrid Imaging 2020 4:10

    Content type: Original article

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  39. According to published data, radiomics features differ between lesions of refractory/relapsing HL patients from those of long-term responders. However, several methodological aspects have not been elucidated yet.

    Authors: Martina Sollini, Margarita Kirienko, Lara Cavinato, Francesca Ricci, Matteo Biroli, Francesca Ieva, Letizia Calderoni, Elena Tabacchi, Cristina Nanni, Pier Luigi Zinzani, Stefano Fanti, Anna Guidetti, Alessandra Alessi, Paolo Corradini, Ettore Seregni, Carmelo Carlo-Stella…

    Citation: European Journal of Hybrid Imaging 2020 4:9

    Content type: Original article

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  40. Response assessment to definitive non-surgical treatment for head and neck squamous cell carcinoma (HNSCC) is centered on the role of 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography ...

    Authors: P. Bonomo, A. Merlotti, S. Morbelli, V. Berti, C. Saieva, F. Bergesio, A. Bacigalupo, L. Belgioia, C. Franzese, E. Lopci, A. Casolo, E. D’Angelo, D. Alterio, L. Travaini, L. Berretta, V. Pirro…

    Citation: European Journal of Hybrid Imaging 2020 4:8

    Content type: Original article

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  41. Simultaneous cardiovascular imaging with positron emission tomography (PET) and magnetic resonance imaging (MRI) requires tools such as radio frequency (RF) phased arrays to achieve high temporal and spatial r...

    Authors: Adam Farag, R. Terry Thompson, Jonathan D. Thiessen, Heather Biernaski, Frank S. Prato and Jean Théberge

    Citation: European Journal of Hybrid Imaging 2020 4:7

    Content type: Original article

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  42. PET/MRI has a high potential in oncology imaging, especially for tumor indications where high soft tissue contrast is crucial such as genitourinary tumors. One of the challenges for PET/MRI acquisition is hand...

    Authors: Ken Kudura, Tobias Oblasser, Daniela A. Ferraro, Caecilia E. Mader, Lars Husmann, Kerstin Friedrich, Edwin E. G. W. ter Voert and Irene A. Burger

    Citation: European Journal of Hybrid Imaging 2020 4:6

    Content type: Original article

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  43. Iodine 123-radiolabeled 2β-carbomethoxy-3β-(4-iodophenyl)-N-(3-fluoropropyl) nortropane (123I-FP-CIT) SPECT can be performed to distinguish degenerative forms of movement disorders/parkinsonism/tremor from other ...

    Authors: Rachid Fahmi, Günther Platsch, Alexandre Bani Sadr, Sylvain Gouttard, Stephane Thobois, Sven Zuehlsdorff and Christian Scheiber

    Citation: European Journal of Hybrid Imaging 2020 4:5

    Content type: Original article

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  44. Clinically non-functioning pituitary macroadenomas (NFMA) have been reported to express somatostatin receptors (SSTR), but results are inconsistent across different studies. This may be related to limited sens...

    Authors: Tessel M. Boertien, Jan Booij, Charles B. L. M. Majoie, Madeleine L. Drent, Alberto M. Pereira, Nienke R. Biermasz, Suat Simsek, Ronald Groote Veldman, Marcel P. M. Stokkel, Peter H. Bisschop and Eric Fliers

    Citation: European Journal of Hybrid Imaging 2020 4:4

    Content type: Short communication

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