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Table 5 Sensitivity and specificity

From: ROC study and SUV threshold using quantitative multi-modal SPECT for bone imaging

Modality

Sensitivity (%)

95% CI

Specificity (%)

95% CI

F3D

68.29

64.8–71.6

88.96

87.1–90.6

xB

72.76

69.4–75.9

95.28

94.0–96.4

F3D/CT

81.71

78.7–84.4

93.91

92.5–95.1

xB/CT

82.38

79.4–85.1

95.66

94.4–96.7

Comparison of area under the curve (AUC)

 Modality

AUC

SEa

95% CIb

Sample size

 F3D

0.786

0.0114

0.768 to 0.804

2052

 F3D/CT

0.878

0.0092

0.863 to 0.892

Positive group

 F3D “Truth”

0.994

0.00234

0.989 to 0.997

738

 xB

0.84

0.0105

0.824 to 0.856

Negative group

 xB/CT

0.89

0.0089

0.876 to 0.903

1314

 xB “Truth”

0.988

0.00329

0.982 to 0.992

 
  1. aHanley and McNeil (1982, 1983)
  2. bBinomial exact