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European Journal of Hybrid Imaging

EJNMMI Multimodality Journal

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  1. [18F]PSMA-1007 is a prostate specific membrane antigen (PSMA) ligand for positron emission tomography (PET) imaging of prostate cancer. Current guidelines recommend imaging 90–120 min after injection but strong d...

    Authors: Erland Hvittfeldt, Ulrika Bitzén, David Minarik, Jenny Oddstig, Berit Olsson and Elin Trägårdh
    Citation: European Journal of Hybrid Imaging 2023 7:9
    Content type: Original article Published on:

  2. In patients with increasing PSA and suspicion for prostate cancer, but previous negative biopsies, PET/MRI is used to test for tumours and target potential following biopsy. We aimed to determine different PSM...

    Authors: Borjana Bogdanovic, Esteban L. Solari, Alberto Villagran Asiares, Sandra van Marwick, Sylvia Schachoff, Matthias Eiber, Wolfgang A. Weber and Stephan G. Nekolla
    Citation: European Journal of Hybrid Imaging 2023 7:8
    Content type: Original article Published on:

  3. Prostate cancer treatment response may be automatically quantified using a molecular imaging analysis platform targeting prostate-specific membrane antigen (PSMA).

    Authors: Sai Duriseti, Gholam Berenji, Sonny Tsai, Matthew Rettig and Nicholas G. Nickols
    Citation: European Journal of Hybrid Imaging 2023 7:7
    Content type: Original article Published on:

  4. Merkel Cell Carcinoma (MCC) is a rare primary cutaneous cancer with aggressive behaviour and poor prognosis. Although MCC cells express somatostatin receptors (SSTR), SSTR-targeted PET/CT is not routinely perf...

    Authors: Cristiano Pini, Giovanni Matassa, Fabrizia Gelardi and Lidija Antunovic
    Citation: European Journal of Hybrid Imaging 2023 7:6
    Content type: Case report Published on:

  5. Texture features reflecting tumour heterogeneity enable us to investigate prognostic factors. The R package ComBat can harmonize the quantitative texture features among several positron emission tomography (PET) ...

    Authors: Masao Watanabe, Ryo Ashida, Chisato Miyakoshi, Shigeki Arizono, Tsuyoshi Suga, Shotaro Kanao, Koji Kitamura, Takahisa Ogawa and Reiichi Ishikura
    Citation: European Journal of Hybrid Imaging 2023 7:5
    Content type: Original article Published on:

  6. Autonomously functioning thyroid nodules (AFTNs) are treated with iodine-131 (I-131) therapy, which increases the risk of permanent hypothyroidism; however, the risk can be reduced by separately estimating the...

    Authors: Won Woo Lee, Yoo Sung Song and Young So
    Citation: European Journal of Hybrid Imaging 2023 7:4
    Content type: Case Report Published on:

  7. The primary aims of this study were to compare in patients with esophageal or esophagogastric junction cancers the potential of 68Ga-NODAGA-RGD PET/CT with that of 18F-FDG PET/CT regarding tumoral uptake and dist...

    Authors: Matthieu Dietz, Vincent Dunet, Styliani Mantziari, Anastasia Pomoni, Ricardo Dias Correia, Nathalie Testart Dardel, Sarah Boughdad, Marie Nicod Lalonde, Giorgio Treglia, Markus Schafer, Niklaus Schaefer and John O. Prior
    Citation: European Journal of Hybrid Imaging 2023 7:3
    Content type: Original article Published on:

  8. Positron emission tomography/computed tomography (PET/CT) using radiotracers that bind to the prostate-specific membrane antigen (PSMA) is mainly used in biochemical recurring prostate cancer. The aim of our s...

    Authors: Irina Vierasu, Gaetan Van Simaeys, Nicola Trotta, Simon Lacroix, Guy Bormans, Simone Albisinni, Thierry Quackels, Thierry Roumeguère and Serge Goldman
    Citation: European Journal of Hybrid Imaging 2023 7:2
    Content type: Original Article Published on:

  9. Erdheim-Chester disease (ECD) is a rare histiocytosis due to proto-oncogene mutations, primarily affecting the long bones and possibly being treated by novel targeted therapies. 18F-FDG PET is a reference techniq...

    Authors: Saifeddine Melki, Thomas Moulinet, Antoine Verger, Pierre-Yves Marie, Laetitia Imbert and Achraf Bahloul
    Citation: European Journal of Hybrid Imaging 2023 7:1
    Content type: Case report Published on:

  10. Metabolic tumor volume (MTV) and total lesion glycolysis (TLG) are volumetric parameters derived from 18F-FDG PET/CT, suggested to have a prognostic value in cancer patients. Our study aimed to test whether these...

    Authors: Hemat A. Mahmoud, Walaa Oteify, Hussein Elkhayat, Ahmed M. Zaher, Taha Zaki Mohran and Nesreen Mekkawy
    Citation: European Journal of Hybrid Imaging 2022 6:37
    Content type: Original Article Published on:

  11. The postulated benefits of the ketogenic diet in the management of multiple medical conditions have seen more patients who are in therapeutic ketosis attending 18F-FDG PET scans. This study aimed to investigate t...

    Authors: O. A. Bennett, S. C. Ramsay, E. Malacova, P. Bourgeat, S. J. Goodman, C. J. Dunn, B. M. Robinson, K. Lee and D. A. Pattison
    Citation: European Journal of Hybrid Imaging 2022 6:29
    Content type: Original article Published on:

  12. We report the case of a 72-year-old woman who presented with tuberculous arthritis during the setting of 177Lu-DOTATATE therapy for a grade-2 neuro-endocrine pancreatic tumor with liver metastases. We hypothesize...

    Authors: Sarah Boughdad, Michael Da Mota, Mélanie Mendes De Carvalho, Maria Firsova, John O. Prior and Niklaus Schaefer
    Citation: European Journal of Hybrid Imaging 2022 6:36
    Content type: Case report Published on:

  13. Hyperparathyroidism is an endocrine disorder that may be associated with other metabolic diseases. Non-invasive imaging techniques including [99mTc]Tc-sestamibi single-photon emission computed tomography (SPECT) ...

    Authors: Carmela Nappi, Leandra Piscopo, Michele Klain, Ciro Gabriele Mainolfi, Emilia Vergara, Daniela Adamo, Michele Davide Mignogna and Alberto Cuocolo
    Citation: European Journal of Hybrid Imaging 2022 6:28
    Content type: Case report Published on:

  14. The goal of the study was to evaluate the diagnostic ability of 18F-FBPA PET/CT for malignant tumors. Findings from 18F-FBPA and 18F-FDG PET/CT were compared with pathological diagnoses in patients with malignant...

    Authors: Kayako Isohashi, Yasukazu Kanai, Teruhito Aihara, Naonori Hu, Kentaro Fukushima, Ichiro Baba, Fumitoshi Hirokawa, Ryo Kakino, Tsuyoshi Komori, Keiji Nihei, Jun Hatazawa and Koji Ono
    Citation: European Journal of Hybrid Imaging 2022 6:35
    Content type: Original article Published on:

  15. Patients with lower-limb osteomyelitis (LLOM) may experience major adverse events, such as lower-leg amputations or death; therefore, early diagnosis and risk stratification are essential to improve outcomes. ...

    Authors: Yoshito Nishikawa, Yoshimitsu Fukushima, Sonoko Kirinoki, Gen Takagi, Masaya Suda, Toshio Maki and Shinichiro Kumita
    Citation: European Journal of Hybrid Imaging 2022 6:27
    Content type: Original article Published on:

  16. Being aware of the unusual or rare location of thyroid metastases helps in early diagnosis and proper patient management. Rare metastases (RM) can be missed resulting in diagnostic pitfalls and delayed treatme...

    Authors: Nahla Bashank, Hussein Farghaly, Sara Hassanein, Mohamed Abdel-Tawab, Mohamed Wahman and Hemat Mahmoud
    Citation: European Journal of Hybrid Imaging 2022 6:34
    Content type: Original article Published on:

  17. Lung perfusion using 99mTc-macroaggregated albumin single-photon emission computed tomography (SPECT) and lung computed tomography (CT) is a useful modality for identifying patients with pulmonary artery embolism...

    Authors: Hidenobu Hashimoto, Tsutomu Soma, Sunao Mizumura, Tadashi Kokubo, Rine Nakanishi and Takanori Ikeda
    Citation: European Journal of Hybrid Imaging 2022 6:32
    Content type: Original article Published on:

  18. Recent neuroimaging studies have demonstrated pathological mechanisms related to cerebral neuroplasticity in chronic low back pain (CLBP). Few studies have compared cerebral changes between patients with and w...

    Authors: Erica Negrini Lia, Priscila Colavite Papassidero, Eduardo Barbosa Coelho, Fabíola Dach, Leonardo Alexandre-Santos, Ana Carolina Trevisan, Lucas Emmanuel Lopes e Santos, Jose Henrique Silvah, Vera Lúcia Lanchote, Oscar Della Pasqua and Lauro Wichert-Ana
    Citation: European Journal of Hybrid Imaging 2022 6:26
    Content type: Original article Published on:

  19. Frostbite is a localized cold thermal injury, as a result of tissue exposure to temperatures below freezing point for a prolonged period of time. The spectrum of injury is broad; thus, frostbite injuries may h...

    Authors: Brunela Ronchi, Gustavo Agustin Peña and Albertti Carla
    Citation: European Journal of Hybrid Imaging 2022 6:25
    Content type: Case report Published on:

  20. Positron emission tomography (PET) in combination with magnetic resonance imaging (MRI) could allow inflammatory complications near total knee arthroplasty (TKA) to be studied early in their development. Howev...

    Authors: Caleigh E. Bourdon, Zachary J. Koudys, Brent A. Lanting, C. Thomas Appleton, Jonathan D. Thiessen and Matthew G. Teeter
    Citation: European Journal of Hybrid Imaging 2022 6:31
    Content type: Original article Published on:

  21. Positron emission tomography (PET) combined with a magnetic resonance (MR) scanner (PET/MR) with 18F-fluorodeoxyglucose (FDG) tracer is being used in quite a few nuclear medicine centers. The aim of this study...

    Authors: Brunela Ronchi, Gustavo Agustin Peña and Carlos Sacchi
    Citation: European Journal of Hybrid Imaging 2022 6:24
    Content type: Case report Published on:

  22. Quality and reproducibility of radiomics studies are essential requirements for the standardisation of radiomics models. As recent data-driven respiratory gating (DDG) [18F]-FDG has shown superior diagnostic perf...

    Authors: Daphné Faist, Mario Jreige, Valentin Oreiller, Marie Nicod Lalonde, Niklaus Schaefer, Adrien Depeursinge and John O. Prior
    Citation: European Journal of Hybrid Imaging 2022 6:33
    Content type: Short communication Published on:

  23. Tuberculosis is an endemic disease in India for decades, and its coexistence in the patients with malignancy cannot be ignored. The non-specific uptake of 2-deoxy-2-[fluorine-18] fluoro-d-glucose in active infect...

    Authors: Deepanksha Datta, T. Ravichandran, Rajesh Kumar, Rashim Sharma and Deepak Vedant
    Citation: European Journal of Hybrid Imaging 2022 6:30
    Content type: Case report Published on:

  25. This work aims to study the impact of different SUV variants in terms of mean and maximum measures as well as various normalization methods with respect to body weight, body mass index, body surface area, and ...

    Authors: Eman M. Badawe, Hesham Abdel Gawad, Mohamed S. El-Nagdy and Magdy M. Khalil
    Citation: European Journal of Hybrid Imaging 2022 6:22
    Content type: Original article Published on:

  26. A 42-year-old male with left hip pain was diagnosed of several right femoral and tibial bone tumours. All lesions were osteolytic with sclerotic margins. The symptomatic lesion in the proximal femur also showe...

    Authors: Chiara Pozzessere, Francesco Cicone, Paolo Barberio, Annalisa Papa, Giuseppe Coppolino, Roberto Biagini and Giuseppe Lucio Cascini
    Citation: European Journal of Hybrid Imaging 2022 6:19
    Content type: Case report Published on:

  27. Accurate staging of non-small cell lung cancer is key in treatment planning and prediction of prognosis. We investigated the correlation between the maximum standardized uptake value (SUVmax) retention index (...

    Authors: Toshinari Ema, Hideaki Kojima, Shinji Mizuno, Tatsuo Hirai, Mikako Oka, Hiroshi Neyatani, Kazuhito Funai and Norihiko Shiiya
    Citation: European Journal of Hybrid Imaging 2022 6:21
    Content type: Original article Published on:

  28. Foreign body-type giant cell reaction is typically a biological and immunological reaction to the presence of foreign bodies such as catheters, parasites or biomaterials with a collection of fused macrophages ...

    Authors: Sakib Kazi, Stavros Raptis, Farzad Abbaspour and Wanzhen Zeng
    Citation: European Journal of Hybrid Imaging 2022 6:18
    Content type: Case report Published on:

  29. The detection of occult infections and low-grade inflammation in clinical practice remains challenging and much depending on readers’ expertise. Although molecular imaging, like [18F]FDG PET or radiolabeled leuko...

    Authors: Johannes Schwenck, Manfred Kneilling, Niels P. Riksen, Christian la Fougère, Douwe J. Mulder, Riemer J. H. A. Slart and Erik H. J. G. Aarntzen
    Citation: European Journal of Hybrid Imaging 2022 6:17
    Content type: Review Published on:

  30. The aim of this study was to compare early (15 min) and late (60 min) [18F]FDOPA PET/CT acquisition times in the detection of recurrence/residual disease in medullary thyroid cancer (MTC) patients.

    Authors: Mette Louise Gram Kjærulff, André H. Dias, Peter Iversen, Lars Christian Gormsen and Karin Hjorthaug
    Citation: European Journal of Hybrid Imaging 2022 6:20
    Content type: Short communication Published on:

  31. Large vessel vasculitis (LVV) can be characterized based on symptom severity, and this characterization helps clinicians decide upon treatment approach. Our aim was to compare the imaging findings of combined ...

    Authors: John W. Cerne, Sophia Liu, Muhammad Umair, Ashitha Pathrose, Jackson E. Moore, Bradley D. Allen, Michael Markl, James C. Carr, Hatice Savas, Lisa Wilsbacher and Ryan Avery
    Citation: European Journal of Hybrid Imaging 2022 6:16
    Content type: Original article Published on:

  32. Magnetic resonance imaging (MRI) and 2-[18F]-fluoro-2-deoxy-d-glucose (18F-FDG) Positron Emission Tomography, paired with Computed Tomography (PET/CT) are commonly used modalities in the complicated diagnostic wo...

    Authors: Dennis Jan Willem Hulsen, Cristina Mitea, Jacobus J. Arts, Daan Loeffen and Jan Geurts
    Citation: European Journal of Hybrid Imaging 2022 6:15
    Content type: Original article Published on:

  33. Magnetic resonance imaging (MRI) is recommended by the European Urology Association guidelines as the standard modality for imaging-guided biopsy. Recently positron emission tomography with prostate-specific m...

    Authors: Daniela A. Ferraro, Andreas M. Hötker, Anton S. Becker, Iliana Mebert, Riccardo Laudicella, Anka Baltensperger, Niels J. Rupp, Jan H. Rueschoff, Julian Müller, Ashkan Mortezavi, Marcelo T. Sapienza, Daniel Eberli, Olivio F. Donati and Irene A. Burger
    Citation: European Journal of Hybrid Imaging 2022 6:14
    Content type: Original article Published on:

  34. A 62-year-old man with resected, pathology-proven small bowel neuroendocrine tumor underwent 111In-pentetreotide SPECT/CT, 18F-DOPA PET/CT and 68Ga-HA-DOTATATE PET/CT to assess metastatic disease. The 111In-pe...

    Authors: Katrin Resch, Ryan Hung and Jonathan Abele
    Citation: European Journal of Hybrid Imaging 2022 6:13
    Content type: Case report Published on:

  35. In treatment of neuroendocrine neoplasms (NENs), confirmation of somatostatin receptor expression with 68Ga-DOTA somatostatin analogues is mandatory to determine eligibility for peptide receptor radionuclide ther...

    Authors: Emile B. Veenstra, Adrienne H. Brouwers, Derk Jan A. de Groot, Johannes Hofland, Annemiek M. E. Walenkamp, Tessa Brabander, Wouter T. Zandee and Walter Noordzij
    Citation: European Journal of Hybrid Imaging 2022 6:12
    Content type: Original article Published on:

  36. Neurolymphomatosis is a rare neurological manifestation associated with non-Hodgkin’s lymphoma. Here we present a case of brachial plexus neurolymphomatosis in a patient with relapsed non-Hodgkin’s lymphoma ex...

    Authors: Simon Doran, Gerard Lambe and Afshin Nasoodi
    Citation: European Journal of Hybrid Imaging 2022 6:11
    Content type: Case report Published on:

  38. This is a case of high-risk, aggressive, high-grade medullary B-cell lymphoma presenting with new onset of neurological dysfunction following initial complete response to the standard chemoimmunotherapy. A who...

    Authors: Gerard Lambe, Simon Doran, Ruth Clifford and Afshin Nasoodi
    Citation: European Journal of Hybrid Imaging 2022 6:9
    Content type: Case report Published on:

  39. A 51-year-old male was found with bilateral thyroid nodules on ultrasonography neck imaging. The largest nodule, measuring 23 × 26 × 35 mm, was located in the left lobe and was classified as EU-TIRADS 4. Thyro...

    Authors: Ringo Manta, Wendy Delbart, Ivan Duran Derijckere, Marie Quiriny, Pieter Demetter, Patrick Flamen and Ioannis Karfis
    Citation: European Journal of Hybrid Imaging 2022 6:8
    Content type: Case report Published on:

  40. The concept of personalized medicine has brought increased awareness to the importance of inter- and intra-tumor heterogeneity for cancer treatment. The aim of this study was to explore simultaneous multi-para...

    Authors: Sahar Ahangari, Flemming Littrup Andersen, Naja Liv Hansen, Trine Jakobi Nøttrup, Anne Kiil Berthelsen, Jesper Folsted Kallehauge, Ivan Richter Vogelius, Andreas Kjaer, Adam Espe Hansen and Barbara Malene Fischer
    Citation: European Journal of Hybrid Imaging 2022 6:7
    Content type: Original article Published on:

  41. Digital PET/CT systems make use of a new technology with higher sensitivity and other better technological features than the analog ones. They require adaptation of the trade-off between performance, tracer do...

    Authors: Irina Vierasu, Nicola Trotta, Simone Albisinni, Céline Mathey, Gil Leurquin-Sterk, Simon Lacroix, Gaetan Van Simaeys, Thierry Quackels, Thierry Roumeguère and Serge Goldman
    Citation: European Journal of Hybrid Imaging 2022 6:6
    Content type: Original article Published on:

  42. 18F-NaF positron emission tomography/computed tomography (fluoride PET/CT) is considered the most sensitive technique to detect bone metastasis in prostate cancer (PCa). 68Ga-PSMA-11 (PSMA) PET/CT is increasingly...

    Authors: Naresh Regula, Vasileios Kostaras, Silvia Johansson, Carlos Trampal, Elin Lindström, Mark Lubberink, Victor Iyer, Irina Velikyan and Jens Sörensen
    Citation: European Journal of Hybrid Imaging 2022 6:5
    Content type: Original article Published on:

  43. Positron emission tomography (PET)-derived LV MBF quantification is usually measured in standard anatomical vascular territories potentially averaging flow from normally perfused tissue with those from areas w...

    Authors: Marina Piccinelli, Navdeep Dahiya, Jonathon A. Nye, Russell Folks, C. David Cooke, Daya Manatunga, Doyeon Hwang, Jin Chul Paeng, Sang-Geon Cho, Joo Myung Lee, Hee-Seung Bom, Bon-Kwon Koo, Anthony Yezzi and Ernest V. Garcia
    Citation: European Journal of Hybrid Imaging 2022 6:4
    Content type: Original article Published on:

  44. We present this case series exploring the complementary role of coronary computed tomography angiography (CCTA) to SPECT myocardial perfusion imaging (MPI) in the detection of myocardial necrosis.

    Authors: Rami M. Abazid, Yasmine T. Sallam, Jonathan G. Romsa, James C. Warrington, Cigdem Akincioglu, Sabe De, Nikolaos Tzemos and William C. Vezina
    Citation: European Journal of Hybrid Imaging 2022 6:3
    Content type: Case report Published on:

  45. Positron emission tomography (PET) imaging with amyloid-beta (Aβ) tracers and 2-[18F] fluoro-2-Deoxy-d-glucose (18F-FDG) is extensively employed in Alzheimer’s disease (AD) studies as biomarkers of AD pathology a...

    Authors: Alison Myoraku, Gregory Klein, Susan Landau and Duygu Tosun
    Citation: European Journal of Hybrid Imaging 2022 6:2
    Content type: Original article Published on:

  46. Rubidium-82 positron emission tomography (82Rb PET) MPI is considered a noninvasive reference standard for the assessment of myocardial perfusion in coronary artery disease (CAD) patients. Our main goal was to co...

    Authors: João R. Inácio, Sriraag Balaji Srinivasan, Terrence D. Ruddy, Robert A. deKemp, Frank Rybicki, Rob S. Beanlands, Benjamin J. W. Chow and Girish Dwivedi
    Citation: European Journal of Hybrid Imaging 2022 6:1
    Content type: Original article Published on:

  47. The positron emission tomography (PET) radioligand 18F-THK5351 is now used to evaluate monoamine oxidase B expression in the reactive astrogliosis seen in various central nervous diseases. Traumatic brain injury ...

    Authors: Tetsuhiro Hatakeyama, Kenya Kawakita, Nobuyuki Kawai, Hajime Shishido, Yuka Yamamoto, Yoshihiro Nishiyama and Keisuke Miyake
    Citation: European Journal of Hybrid Imaging 2021 5:26
    Content type: Case report Published on:

  48. Pulmonary embolism is indicated by ventilation/perfusion (V/P) mismatches in ventilation/perfusion scintigraphy. However, other pathologies may also evoke segmental or lobar mismatches. Thus, diagnosis can be ...

    Authors: David Kersting, Christoph Rischpler, Till Plönes, Clemens Aigner, Lale Umutlu, Ken Herrmann and Hubertus Hautzel
    Citation: European Journal of Hybrid Imaging 2021 5:25
    Content type: Case report Published on:

  49. To evaluate the diagnostic and prognostic significance of combined cardiac 18F-fluorodeoxyglucose (FDG) PET/MRI with T1/T2 mapping in the evaluation of suspected cardiac sarcoidosis.

    Authors: Edward Cheung, Sarah Ahmad, Matthew Aitken, Rosanna Chan, Robert M. Iwanochko, Meyer Balter, Ur Metser, Patrick Veit-Haibach, Filio Billia, Yasbanoo Moayedi, Heather J. Ross and Kate Hanneman
    Citation: European Journal of Hybrid Imaging 2021 5:24
    Content type: Original article Published on:

  50. 18F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging (18F-FDG PET/MRI) may improve cancer staging by combining sensitive cancer detection with high-contrast resolution and detail. We co....

    Authors: Amy R. Sharkey, Bert-Ram Sah, Samuel J. Withey, Shaheel Bhuva, Radhouene Neji, Sami Jeljeli, Adrian Green, Gary J. R. Cook and Vicky Goh
    Citation: European Journal of Hybrid Imaging 2021 5:23
    Content type: Original article Published on:
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