Table 1 Patient clinical characteristics
All Patients (n = 155) | Patients without appropriate ICD therapy (n = 112) | Patients with appropriate ICD therapy (n = 43) | p-value | |
|---|---|---|---|---|
Clinical characteristics | ||||
Age | 72 ± 8.9 | 72 ± 8.7 | 71 ± 9.3 | 0.700 |
Male, n(%) | 115 (74) | 79 (71) | 36 (84) | 0.093 |
NYHA functional class, n(%) | ||||
I | 21 (14) | 16 (14) | 5 (12) | 0.817 |
II | 51 (33) | 35 (31) | 16 (37) | |
III/IV | 80 (52) | 59 (53) | 21 (49) | |
Ischemic cardiomyopathy, n(%) | 88 (57) | 60 (54) | 28 (65) | 0.194 |
Devices | ||||
ICD, n(%) | 51 (33) | 36 (32) | 15 (35) | 0.745 |
CRT-D, n(%) | 104 (67) | 76 (68) | 28 (65) | |
Cardiovascular risk factors | ||||
Dyslipidemia, n(%) | 44 (28) | 30 (27) | 14 (33) | 0.475 |
Diabetes, n(%) | 25 (16) | 19 (17) | 6 (14) | 0.648 |
Hypertension, n(%) | 57 (37) | 41 (37) | 16 (37) | 0.945 |
Smoking, n(%) | 35 (23) | 25 (22) | 10 (23) | 0.901 |
Medication | ||||
ACE-I/ARB’s, n(%) | 132 (85) | 97 (87) | 35 (81) | 0.414 |
Diuretics, n(%) | 115 (74) | 79 (71) | 36 (84) | 0.093 |
Beta-blockers, n(%) | 118 (76) | 83 (74) | 35 (81) | 0.341 |
-Sotalol | 5 (4) | 4 (4) | 1 (2) | 1.000 |
Calcium-blockers, n(%) | 77 (50) | 55 (49) | 22 (51) | 0.819 |
Amiodarone, n(%) | 30 (19) | 23 (21) | 7 (16) | 0.548 |
Digoxin, n(%) | 17 (11) | 14 (13) | 3 (7) | 0.325 |
Statin, n(%) | 97 (63) | 70 (63) | 27 (63) | 0.973 |
Anti-diabetic medication, n(%) | 83 (54) | 58 (52) | 25 (58) | 0.478 |
Laboratory results | ||||
Creatinine (mmol/L) | 101 ± 32 | 100 ± 31 | 105 ± 35 | 0.368 |
Hematocrit (%) | 41.6 ± 3.3 | 41.6 ± 3.3 | 41.5 ± 3.5 | 0.887 |