Fig. 8
From: Combined amino acid PET-MRI for identifying recurrence in post-treatment gliomas: together we grow
Sequence of images showing false positive C11 methionine uptake in acute inflammatory pathology: Axial post-contrast T1 MPRAGE (A) in a case of suspected recurrence shows parenchymal enhancement (vertical arrow) suggestive of recurrent lesion with associated enhancement of the overlying bone and soft tissues (horizontal arrow). C11 methionine PET image fused with axial T1 MPRAGE (B) shows tracer uptake along the bone and soft tissues (horizontal arrow) in addition to parenchymal uptake (vertical arrow). Here the uptake in the bone and soft tissues occurred due to osteomyelitis. Follow-up axial post-contrast T1 MPRAGE following chemo/radiotherapy (C) shows reduction in parenchymal enhancement (vertical arrow) with persistent enhancement in bone and soft tissues (horizontal arrow). Sequential axial CT brain images in bone window (D–F) show initial scan (D) with normal bone followed by progressive osteomyelitis in E and excision of the infected bone in F