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EJNMMI Reports

Table 2 Per-quadrant accuracy and interreader agreement results for PSMA PET/MRI and mpMRI for detection of csPCa

From: 68Ga-PSMA-11 PET/MRI versus multiparametric MRI in men referred for prostate biopsy: primary tumour localization and interreader agreement

 

PSMA PET/MRI

mpMRI

p value

AUC (95% CI)

0.80 (0.73, 0.86)

0.77 (0.71, 0.83)

0.56

Sensitivity

66.7%

61.4%

 

Specificity

92.9%

92.9%

 

PPV

84.4%

83.3%

 

NPV

82.9%

80.7%

 

Accuracy

83.3%

81.4%

 

Cohen’s Kappa coefficient* (95% CI)

0.73 (0.61–0.84)

0.65 (0.52–0.79)

 
  1. AUC, area under the receiving operator characteristics curve; CI, confidence interval; csPCa, clinically significant prostate cancer; NPV, negative predictive value; PPV, positive predictive value
  2. *Calculated considering readout scores 1 and 2 as negative and 3, 4 and 5 as positive
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