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Table 1 Patients’ characteristics: including staging, risk stratification and treatment details

From: Rare sites of metastases in patients with differentiated thyroid carcinoma and added value of SPECT/CT over planar whole body radioactive iodine scan

Cases

Age

Sex

Presentation

Histologic type

TNM staging (AJCC, 2018)

 

Risk stratification

Distant metastasis

Cumulative dose (mCi)

Follow-up duration (years)

Disease status

Last observation

1

60

F

Shoulder swelling

FTC

T1bN0M1

IVb

High

Bone and lung

850

5

Regression with complete resolution of RM

Alive with disease

2

59

F

Diminution of vision and Dorsal mass with both LL weakness

FTC

T3N0M1

IVb

High

Bone

400

2

Progression

Alive with disease

3

45

F

Neck swelling

FTC

T3NxM1

II

High

Lung Muscle Renal

600

7

Progression

Alive with disease

4

32

F

Neck swelling

PTC (classic variant)

T4aN1M0

I

Intermediate

No

375

2.5

Complete resolution

Alive free from disease

5

55

M

Iliac mass

FTC

Unknown

IVb

High

Bone

400

3

Stable

Died

6

60

F

Shoulder swelling

FTC

T3bN1M1

IVb

High

Bone, lung and brain

600

4

Stable

Alive with disease

7

42

F

Neck swelling

PTC (classic variant)

T2N0M1

II

High

Bone

300

1

Regression

Alive with disease

8

75

M

Eye scotoma with choroid mass in the eye

FTC

Unknown

IVb

High

Bone, lung, liver and eye

470

3

Regression

Alive with disease

9

79

F

Neck swelling

Insular (poorly differentiated)

T4bN0M0

IVa

High

No

180

3

Regression

Alive with disease

10

75

F

Shoulder swelling

PTC (classic variant

T2N1M1

IVb

High

Lung bone

450

3

Regression

Alive with disease

11

64

M

Neck swelling

PTC (unknown)

T4aN1M1

IVb

High

Renal

470

2.5

Progression

Alive with disease

12

53

M

Solitary brain lesion

PTC (follicular variant)

Unknown

II

High

No

150

1

Regression

Alive with disease

13

48

M

Solitary brain lesion (headache)

PTC (follicular variant)

T1bN0M1

II

High

Bone, lung

450

2

Progression

Died

14

27

F

Neck swelling

PTC (follicular variant)

T1bN1M0

I

Intermediate

No

175

1.5

Complete resolution

Alive free from disease

15

63

M

Dyspnea

PTC (classic variant)

Unknown

IVb

High

Bone trachea

375

7

Progression

Died

  1. FTC follicular thyroid carcinoma, PTC papillary thyroid carcinoma