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Fig. 4 | European Journal of Hybrid Imaging

Fig. 4

From: Comparison of integrin αvβ3 expression with 68Ga-NODAGA-RGD PET/CT and glucose metabolism with 18F-FDG PET/CT in esophageal or gastroesophageal junction cancers

Fig. 4

68Ga-NODAGA-RGD PET/CT (A), PET (B, D) and CT (C) and 18F-FDG PET/CT (E), PET (F, H) and CT (G) axial views of a primary lesion (asterisks) in a 53-year-old participant with esophageal squamous cell carcinoma. Note intense homogenous uptake in the primary lesion on 18F-FDG PET/CT (SUVmax 12.1 g/mL, metabolic tumor volume 2.54 cm3), whereas the primary lesion demonstrates a different uptake pattern in the corresponding 68Ga-NODAGA-RGD PET/CT image: a weaker and more heterogeneous uptake (SUVmax 5.1 g/mL), seen mostly in the periphery of the tumor, with a slight extension in perilesional structures (arrows), and a larger metabolic tumor volume (metabolic tumor volume 5.35 cm3)

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