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Table 1 Main clinical and hemodynamic data of the overall population with the corresponding age-stratified comparisons between young (≤ 40 years old), middle-aged (41 to 60 years old), and older (> 60 years old) adults

From: Volume of the proximal half of the thoracic aorta is the most comprehensive FDG-PET/CT indicator of arterial aging throughout adulthood

 

Overall

(n = 79)

Young

(n = 22)

Middle-aged

(n = 19)

Old

(n = 38)

P-value

Women

38 (48%)

11 (50%)

13 (68%)

14 (37%)

0.080

Age (years)

59 [38–70]

31 [27–38]

55 [48–57]*

71 [65–75]*†

 < 0.001

BMI (kg/m2)

27.2 [23.4–30.5]

25.2 [22.1–29.0]

29.1 [26.9–32.7]

27.3 [23.9–29.3]

0.129

Obesity

22 (28%)

5 (23%)

8 (42%)

9 (24%)

0.316

Hypertension

35 (43%)

3 (14%)

5 (26%)

27 (71%)*†

 < 0.001

Diabetes

7 (9%)

1 (5%)

0 (0%)

6 (16%)

0.169

Dyslipidemia

33 (42%)

2 (9%)

6 (32%)

25 (66%)*†

 < 0.001

Smoking

20 (25%)

9 (41%)

3 (16%)

8 (21%)

0.128

History of CV disease

11 (14%)

0 (0%)

2 (11%)

9 (24%)

0.022

Heart rate (bpm)

64 [56–73]

61.5 [55–72]

68 [56–79]

63.5 [57–70]

0.615

Systolic BP (mmHg)

125 [116–137]

117 [112–122]

127 [119–137]*

132 [121–147]*

 < 0.001

Diastolic BP (mmHg)

71 [64–79]

66 [63–72]

74 [67–77]

72 [64–83]

0.147

Pulse BP (mmHg)

54 [48–64]

50 [43–53]

56 [48–64]*

58 [53–76]*

0.002

PWV (m/s)

7.5 [6.1–9.7]

6.3 [5.9–6.7]

7.2 [6.7–9.3]*

8.6 [7.3–11.5]*

0.001

  1. Continuous variables expressed as medians [with interquartile ranges] and categorical variables as n (%)
  2. BMI: body mass index; bpm: beats per minute; CV: cardiovascular; BP: blood pressure; PWV: Pulse wave velocity
  3. *significant difference vs. young adults; †significant difference vs. middle-aged adults