Table 1 Exclusion criteria

Previous or current disorders that might interfere with performance or safety of study procedures

Age < 18 years

Pregnant or breastfeeding women

Any contraindication to MRI (pacemakers, neurostimulators, some implantable devices, some metallic implants, claustrophobia)^a

Adults with mental incapacities

Inability to follow the procedures of the study e.g. due to language problems, psychological disorders, dementia, etc. of the participant

COPD or asthma with severe obstruction: severe obstructive patients (FEV1 < 50% of predicted value), Hypoxemia (SaO₂ < 94% AA), history or physical signs of right heart failure

History or physical signs of right or left cardiac failure

History or physical signs of pulmonary hypertension

History or physical signs of active coronary artery disease

Pulmonary graft

Immunocompromised patients

Known or suspected non-compliance with appointments, alcoholism, drug addiction or alike

Enrolment of the investigator, his/her family members, employees and other dependent persons