Lung CT stabilization with high-frequency non-invasive ventilation (HF-NIV) and breath-hold (BH) in lung nodule assessment by PET/CT

EJNMMI Reports

Table 2 Characteristics of lung nodules

	FB	HF-NIV	BH	p value
Number of nodules	191***	368***	422	< 0.001
l_axis (mm)	3.2 ± 2.4***	2.6 ± 1.9	2.4 ± 2.1	< 0.001
s_axis (mm)	2.1 ± 1.7***	1.6 ± 1.2	1.5 ± 3	< 0.001
Nodule volume (mm³)	49.8 ± 202.1^†	23 ± 112	22.6 ± 105.1	0.040
Solid/sub-solid pattern	147 (76.9%)/44 (23%)**	296 (80.4%)/72 (19.6%)**	294 (69.7%)/128 (30.3%)	0.002

BH breath hold, HF-NIV high frequency non-invasive ventilation, FB free breathing
***p < 0.001, **p < 0.01, ^†p < 0.1 versus BH