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EJNMMI Reports

Table 3 Difference in degree of uptake between 18F-fluorodeoxyglucose and 18F-fluoroestradiol

From: Head-to-head comparison of 18F-FDG and 18F-FES PET/CT for initial staging of ER-positive breast cancer patients

 

Median (interquartile range)

p-value

18F-flurodeoxyglucose

18F-fluoroestradiol

All lesion

SUVmax

5.68 (3.41–10.03)

5.38 (2.55–10.60)

0.646

T/N ratio

2.635 (1.58–4.79)

3.335 (1.61–6.38)

0.016

IDC cell type

SUVmax

6.23 (3.63–10.34)

5.23 (2.29–10.6)

0.138

T/N ratio

3.14 (1.63–5.05)

3.26 (1.55–6.43)

0.144

ILC cell type

SUVmax

2.15 (1.24–4.25)

4.75 (2.76–8.78)

0.028

T/N ratio

0.96 (0.55–1.79)

3.30 (1.92–6.09)

0.015

Allred score

SUVmax

4.06 (2.20–6.42)

6.51 (3.51–9.69)

0.003

T/N ratio

1.92 (1.22–2.96)

3.57 (1.97–5.89)

 < 0.001

Score < 7

SUVmax

9.49 (5.22–17.66)

1.72 (1.34–2.79)

 < 0.001

T/N ratio

4.96 (3.00–9.37)

1.48 (0.81–2.03)

 < 0.001

Luminal Subtype

Luminal A

   

SUVmax

1.92 (1.33–11.13)

3.44 (2.76–6.77)

0.019

T/N ratio

0.86 (0.56–0.96)

2.18 (1.92–3.98)

0.004

Luminal B

SUVmax

7.39 (3.79–11.13)

5.43 (2.34–10.60)

0.008

T/N ratio

3.56 (1.69–5.05)

3.24 (1.40–6.38)

0.718

  1. IDC Invasive ductal carcinoma, ILC Invasive lobular carcinoma, SUVmax Maximal standardize uptake value, T/N ratio Tumor-to-normal ratio
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