Table 4 Factors associated with degree of uptake in 18F-fluorodeoxyglucose and 18F-fluoroestradiol PET/CT
Factor | 18F-fluorodeoxyglucose | 18F-fluoroestradiol | ||
|---|---|---|---|---|
Correlation coefficient (95% C.I.) | p-value | Correlation coefficient (95% C.I.) | p-value | |
Age (year) | 0.01 (− 0.14, 0.16) | 0.937 | 0.12 (− 0.08, 0.31) | 0.233 |
BMI (kg/m2) | 0.16 (− 0.37, 0.69) | 0.551 | 0.45 (− 0.21, 1.12) | 0.181 |
Menopause status | ||||
No | Ref | Ref | ||
Yes | − 0.33 (− 5.30, 4.65) | 0.898 | 5.74 (− 0.54, 12.01) | 0.073 |
Cell type | ||||
Invasive ductal carcinoma | Ref | Ref | ||
Invasive lobular carcinoma | − 5.32 (− 11.48, 0.84) | 0.090 | 1.46 (− 4.26, 7.19) | 0.616 |
Invasive micropapillary carcinoma | − 0.95 (− 10.24, 8.33) | 0.841 | − 0.64 (− 8.24, 6.95) | 0.868 |
Mucinous carcinoma | − 5.04 (− 14.18, 4.10) | 0.280 | 26.65 (19.28, 34.02) | < 0.001 |
Intensity of ER expression | ||||
Weak | Ref | Ref | ||
Moderate | − 1.87 (− 10.22, 6.48) | 0.660 | 0.34 (− 10.21, 10.90) | 0.949 |
Strong | − 3.82 (− 9.04, 1.40) | 0.152 | 5.83 (− 0.56, 12.22) | 0.074 |
Proportion of ER expression | ||||
< 1% | – | – | ||
1-10% | Ref | Ref | ||
11-33% | 0.22 (− 10.34, 10.79) | 0.967 | − 1.33 (− 14.63, 11.96) | 0.844 |
34-66% | − 0.64 (− 8.03, 6.75) | 0.865 | 3.20 (− 6.00, 12.41) | 0.495 |
> 67% | − 2.39 (− 7.87, 3.09) | 0.393 | 5.84 (− 0.75, 12.43) | 0.082 |
Allred Score | ||||
< 7 | Ref | Ref | ||
7–8 | − 3.60 (− 8.38, 1.18) | 0.140 | 5.90 (− 0.0005, 11.81) | 0.050 |
Luminal | ||||
A | Ref | Ref | ||
B | 2.76 (1.10, 11.92) | 0.018 | − 1.39 (− 5.11, 2.34) | 0.465 |
Ki-67 | 0.11 (0.01, 0.20) | 0.025 | − 0.06 (− 0.12, 0.01) | 0.096 |