Table 4 Sensitivity, specificity, NPV, PPV, and Accuracy for the diagnosis of lung metastases per patient with different techniques

FDG PET (all values in percentages) (95% confidence interval in brackets)

Sensitivity

47 (28, 66)

50 (31, 69)

47 (28, 66)

Specificity

96 (88, 99)

96 (88, 99)

97 (90, 100)

NPV*

81 (71, 89)

82 (72, 89)

81 (71, 89)

PPV*

82 (57, 96)

83 (59, 96)

88 (62, 98)

Accuracy*

81 (72, 88)

82 (73, 89)

82 (73, 89)

FDG PET/lCT (all values in percentages) (95% confidence interval in brackets)

Sensitivity

77 (58, 90)

80 (61, 92)

83 (65, 94)

Specificity

80 (69, 89)

80 (69, 89)

86 (75, 93)

NPV*

89 (78, 95)

90 (80, 96)

92 (83, 97)

PPV*

62 (45, 78)

63 (46, 78)

71 (54, 85)

Accuracy*

79 (70, 87)

80 (71, 87)

85 (76, 91)

FDG PET/dCT (all values in percentages) (95% confidence interval in brackets)

Sensitivity

100 (88, 100)

100 (88, 100)

100 (88, 100)

Specificity

57 (45, 69)

54 (42, 66)

59 (46, 70)

NPV*

100 (91, 100)

100 (91, 100)

100 (91, 100)

PPV*

50 (37, 63)

48 (35, 61)

51 (37, 64)

Accuracy*

70 (60, 79)

68 (58, 77)

71 (61, 80)

FDG PET/CAD (all values in percentages) (95% confidence interval in brackets)

Sensitivity

93 (78, 99)

97 (83, 100)

97 (83, 100)

Specificity

64 (52, 75)

64 (52, 75)

64 (52, 75)

NPV*

96 (85, 99)

98 (88, 100)

98 (88, 100)

PPV*

53 (39, 67)

54 (40, 67)

54 (40, 67)

Accuracy*

73 (63, 81)

74 (64, 82)

74 (64, 82)

All three readers combined (all values in percentages) (95% confidence interval in brackets)

Sensitivity

48 (37, 59)

80 (70, 88)

100 (96, 100)

96 (89, 99)

Specificity

96 (93, 98)

82 (76, 87)

57 (50, 63)

64 (57, 71)

NPV*

81 (76, 86)

91 (85, 94)

100 (97, 100)

97 (93, 99)

PPV*

84 (71, 93)

65 (56, 74)

50 (42, 57)

53 (45, 61)

Accuracy*

82 (77, 86)

81 (76, 86)

70 (64, 75)

74 (68, 79)