Comparative analysis of two timepoints on [18F]FAPI-42 PET/CT in various cancers

EJNMMI Reports

Table 2 Head-to-Head Comparison of SUV_max between Early [¹⁸F]FAPI-42 PET and 2-[¹⁸F]FDG PET

Caner type	State	Early [¹⁸F]FAPI-42 PET/CT					2-[¹⁸F]FDG PET/CT
Caner type	State	Primary lesion	LN metastasis(1)	LN metastasis(2)	Other metastasis	Location	Primary lesion	LN metastasis(1)	LN metastasis(2)	Other metastasis	Location
Breast cancer	Recurrence				2.3	Bone				2.5	Bone
Colorectal cancer	Before surgery	7.1	6.1	6.2*	6.3, 3.8	Liver	14.3	3.2	4.1	12.6, 5.7	Liver
Colorectal cancer	Before surgery	6.3					7.9
Cholangiocarcinoma	Before treatment	7.7			6.5, 5.7	Kidney	5.7			2.9, 3.0	Kidney
Esophagus cancer	Before surgery	11.5	7.6	6.8*			12.6	5.2	7.8
Liver cancer	Recurrence	7.1					6.5
NSCLC	Before Treatment	5.3	4.6	4.4*			5.1	2.4	2.5
NSCLC	Before surgery	5	10.9	10.1*			7.6	5.1	5
Prostate cancer	Before surgery	7.7					4.8
Thyroid cancer	SIR⁺				7.6	Bone				8.4	Bone
Thyroid cancer	SIR⁺		8.8					7.9

*Number of detected LN metastases is more than 3, and 2 major sites are shown here
Patient with multifocal pulmonary lesions, and the lesion with the largest diameter was shown here
⁺Follow-up examination indicate structural incomplete disease after thyroidectomy and radioactive iodine treatment
LN Lymph node; NSCLC Non-small cell lung cancer; SIR Structural incomplete disease