Table 1 Patient overview
Patient number | 1 | 2 | 3 |
|---|---|---|---|
Age | 81 | 75 | 64 |
Sex | Female | Female | Male |
Histology | DLBCL | DLBCL | DLBCL |
Number of lesions | 1 | 5 (plus 1 pituitary adenoma) | 1 |
Biopsy location | Right basal ganglia | Right nucleus lentifomis | Right basal ganglia |
First line treatment | R-MPV × 5 + maintenance Temozolomide | R-MPV × 7 + maintenance Temozolomide | MATRix × 4 + BCNU/Thiotepa ASCT |
MRI evaluation after 4 or 5 cycles of treatment | Complete remission | Partial remission | Partial remission |
Relapse | yes (13 months after initial diagnosis) | yes (4 months after initial diagnosis) | No (16 months after initial diagnosis) |
IELSG score | 3 | 4 | 4 |
MSKCC score | 2 | 3 | 3 |
ECOG PS | 2 | 2 | 2 |