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Table 2 NSE below reference value, above reference value, and comparison of factors

From: Association between PET–CT accumulation in the hypothalamic/pituitary regions and neuron-specific enolase/primary tumor in limited-stage small cell lung cancer: a case-controlled retrospective study

 

NSE < 16.3 ng/mL

NSE ≥ 16.3 ng/mL

P value

Number of cases

6

13

 

Age

73.5 years

71.0 years

0.33

Sex

Male: 5

Male: 8

0.60

Female: 1

Female: 5

White blood cells

7.4 × 103/µL

6.8 × 103/µL

0.73

Red blood cells

4.47 × 106/µL

4.46 × 106/µL

0.90

Hemoglobin

13.3 g/dL

13.9 g/dL

0.43

Platelets

242 × 103/µL

285 × 103/µL

0.28

Total protein

7.2 g/dL

7.3 g/dL

0.86

Albumin

4.2 g/dL

4.0 g/dL

0.57

CEA

2.85 ng/mL

4.80 ng/mL

0.27

NSE

12.1 ng/mL

34.1 ng/mL

< 0.01

Hypothalamus and pituitary gland SUVmax (all cases)

2.95

4.10

0.03

Total volume of hypothalamic/pituitary region

0.60 mL

0.45 mL

0.10

TLG of hypothalamic/pituitary region

1.32 SUV × mL

1.23 SUV × mL

0.63

SUVmax of the primary tumor

14.3

13.0

0.43

Volume of the primary tumor

14.9 mL

37.5 mL

0.13

TLG of the primary tumor

114.0 SUV × mL

199.0 SUV × mL

0.24

Maximum diameter of primary tumor

28 mm

49 mm

0.16

SUVmax of the lymph node metastases

9.80

13.5

0.44

Volume of lymph node metastases

3.82 mL

31.9 mL

0.04

TLG of the lymph node metastases

22.8 SUV × mL

181.4 SUV × mL

0.03

Total tumor volume of primary tumor and lymph node metastases

17.8 mL

98.9 mL

< 0.01

Total TLG of primary tumor and lymph node metastases

126.6 SUV × mL

701.2 SUV × mL

< 0.01

  1. CEA, Carcinoembryonic antigen; NSE, neuron-specific enolase; PET–CT, positron emission tomography–computed tomography; SUVmax, maximum standardized uptake value; TLG, total lesion glycolysis