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Table 5 Diagnostic performance indices for 18F-FDG PET/CT and BMB in detection of BMI in Pediatric lymphoma

From: 18F-FDG PET/CT versus bone marrow biopsy in detecting bone marrow infiltration in initial staging of pediatric lymphoma

Pathology

Modality

Sensitivity

Specificity

PPV

NPV

Accuracy

Hodgkin’s lymphoma

PET/CT

(95%CI)

86

(76–96)

90

(81–99)

60

(46–74)

97

(93–102)

89

(81–98)

BMB

(95%CI)

71

(59–84)

48

(33–62)

19

(8–30)

90

(82–99)

51

(37–65)

Non-Hodgkin’s lymphoma

PET/CT

(95%CI)

75

(56–94)

73

(53–93)

67

(45–88)

80

(62–98)

74

(54–93)

BMB

(95%CI)

88

(73–102)

73

(53–93)

70

(49–91)

89

(75–103)

79

(61–97)

Total

PET/CT

(95%CI)

80

(70–90)

86

(78–95)

63

(52–75)

94

(88–100)

85

(76–93)

BMB

(95%CI)

80

(70–90)

53

(41–65)

33

(22–45)

90

(83–97)

59

(47–71)