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Table 1 Baseline clinical parameters

From: Combined simultaneous FDG-PET/MRI with T1 and T2 mapping as an imaging biomarker for the diagnosis and prognosis of suspected cardiac sarcoidosis

 

All patients (n = 42)

Cardiac sarcoidosis (n = 13)

Not cardiac sarcoidosis (n = 29)

P value

Age, year

53 ± 13

59 ± 11

50 ± 14

0.039

Women, n (%)

14 (33%)

4 (31%)

10 (34%)

0.99

Body surface area, m2

2.0 ± 0.2

2.0 ± 0.2

2.0 ± 0.2

0.30

Systolic blood pressure, mmHg

124 ± 19

129 ± 23

121 ± 17

0.24

Diastolic blood pressure, mmHg

75 ± 10

79 ± 10

74 ± 10

0.20

Symptomatic, n (%)

24 (57%)

10 (77%)

14 (48%)

0.10

Final diagnosis

Cardiac sarcoidosis

13 (31%)

13 (100%)

–

 

Extra-cardiac sarcoidosis with no cardiac involvement

10 (24%)

–

10 (34%)

 

Myocarditis

7 (17%)

–

7 (24%)

 

Non-ischemic/inflammatory cardiomyopathy

12 (29%)

–

12 (41%)

 

Risk factors

Smoking history, n (%)

14 (33%)

7 (54%)

7 (24%)

0.08

Hypertension, n (%)

19 (45%)

7 (54%)

12 (41%)

0.52

Diabetes mellitus, n (%)

10 (24%)

2 (15%)

8 (28%)

0.47

Hypercholesterolemia, n (%)

18 (43%)

7 (54%)

11 (38%)

0.50

Medications

Beta blocker, n (%)

22 (53%)

7 (54%)

15 (52%)

0.99

ACE inhibitor, n (%)

12 (29%)

4 (31%)

8 (28%)

0.99

ARB, n (%)

6 (14%)

2 (15%)

4 (14%)

0.99

Immune suppression therapy, n (%)

6 (14%)

2 (15%)

4 (14%)

0.99

Corticosteroids, n (%)

6 (14%)

2 (15%)

4 (14%)

0.99

Methotrexate, n (%)

2 (5%)

1 (8%)

1 (3%)

0.53

  1. Variables are presented as mean ± standard deviation or number with percentage in parentheses. P values are for the comparison between patients with cardiac sarcoidosis and those without. Final diagnosis of cardiac sarcoidosis was established using modified 2006 revised Japanese Ministry of Health and Welfare (JMHW) guideline as the reference standard
  2. ACE angiotensin-converting enzyme, ARB angiotensin II receptor blockers