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European Journal of Hybrid Imaging

EJNMMI Multimodality Journal

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  1. The original publication of this article El Mahdiui et al., 2019 contained 2 errors that could not be updated prior to publication. The correct and incorrect information is shown below for clarification. The c...

    Authors: Mohammed El Mahdiui, Jeff M. Smit, Alexander R. van Rosendael, Victoria Delgado, Nina Ajmone Marsan, J. Wouter Jukema, Arthur J. H. A. Scholte and Jeroen J. Bax
    Citation: European Journal of Hybrid Imaging 2019 3:19
    Content type: Correction Published on:

    The original article was published in European Journal of Hybrid Imaging 2019 3:14

  2. Bioactive glass has been successfully used for surgical treatment of chronic infections in bone and bone cavities. Besides infection control, new bone formation is induced by the bioactive glass which is consi...

    Authors: Adriana J. Timmermans, Jasper J. Quak, Petronella J. Hagen and David R. Colnot
    Citation: European Journal of Hybrid Imaging 2019 3:18
    Content type: Case report Published on:

  4. FDG-PET/CT is increasingly used for oncologic and inflammatory diseases. Focal incidental FDG uptake occurs rarely in breast tissue but has often significant consequences. This study aimed to systematically re...

    Authors: Else Marie Aarstad, Petter Nordhaug, Mohammad Naghavi-Behzad, Lisbet Brønsro Larsen, Oke Gerke and Malene Grubbe Hildebrandt
    Citation: European Journal of Hybrid Imaging 2019 3:16
    Content type: Review Published on:

  5. Positron emission tomography (PET) is the non-invasive reference standard for myocardial blood flow (MBF) quantification. Hybrid PET-MR allows simultaneous PET and cardiac magnetic resonance (CMR) acquisition ...

    Authors: Muhummad Sohaib Nazir, Sarah-May Gould, Xenios Milidonis, Eliana Reyes, Tevfik F. Ismail, Radhouene Neji, Sébastien Roujol, Jim O’Doherty, Hui Xue, Sally F. Barrington, Tobias Schaeffter, Reza Razavi, Paul Marsden, Peter Kellman, Sven Plein and Amedeo Chiribiri
    Citation: European Journal of Hybrid Imaging 2019 3:15
    Content type: Original article Published on:

  6. Cardiovascular imaging using hybrid positron emission tomography (PET) and magnetic resonance imaging (MRI) requires a radio frequency phased array resonator capable of high acceleration factors in order to ac...

    Authors: Adam Farag, R. Terry Thompson, Jonathan D. Thiessen, John Butler, Frank S. Prato and Jean Théberge
    Citation: European Journal of Hybrid Imaging 2019 3:13
    Content type: Original article Published on:

  7. Even though implantable cardioverter defibrillator (ICD) implantation for primary prevention has shown to reduce the risk of sudden cardiac death in chronic heart failure patients with reduced left ventricular...

    Authors: Mohammed El Mahdiui, Jeff M. Smit, Alexander R. van Rosendael, Victoria Delgado, Nina Ajmone Marsan, J. Wouter Jukema, Arthur J. H. A. Scholte and Jeroen J. Bax
    Citation: European Journal of Hybrid Imaging 2019 3:14
    Content type: Original article Published on:

    The Correction to this article has been published in European Journal of Hybrid Imaging 2019 3:19

  8. [F-18]fluorodeoxyglucose positron emission tomography/computed tomography is routinely used for assessing Takayasu arteritis patients. However, extra-vessel [F-18]fluorodeoxyglucose uptake has not been evaluated ...

    Authors: Junichi Tsuchiya, Daisuke Tezuka, Yasuhiro Maejima, Hyeyeol Bae, Takumi Oshima, Tomohiro Yoneyama, Kenzo Hirao, Mitsuaki Isobe and Ukihide Tateishi
    Citation: European Journal of Hybrid Imaging 2019 3:12
    Content type: Original article Published on:

  9. An increasing number of Nuclear Medicine sites in Europe are using cardiac-centered gamma cameras for myocardial perfusion scintigraphy (MPS). Three cardiac-centered gamma cameras are currently the most freque...

    Authors: Fabien Hyafil, Alessia Gimelli, Riemer H. J. A. Slart, Panagiotis Georgoulias, Christoph Rischpler, Mark Lubberink, Roberto Sciagra, Jan Bucerius, Denis Agostini and Hein J. Verberne
    Citation: European Journal of Hybrid Imaging 2019 3:11
    Content type: Guideline Published on:

  10. We investigated the clinical performance of a quantitative multi-modal SPECT/CT reconstruction platform for yielding radioactivity concentrations of bone imaging with 99mTc-methylene diphosphonate (MDP) or 99mTc-...

    Authors: A. H. Vija, P. A. Bartenstein, J. W. Froelich, T. Kuwert, H. Macapinlac, C. P. Daignault, N. Gowda, O. Hadjiev, J. Hephzibah, P. Huang, H. Ilhan, A. Jessop, M. Cachovan, J. Ma, X. Ding, D. Spence…
    Citation: European Journal of Hybrid Imaging 2019 3:10
    Content type: Original article Published on:

  11. Diagnosis and evaluation of cardiac sarcoidosis (CS) are mainly based on the combined use of cardiac magnetic resonance imaging (CMR) and 18F fludeoxyglucose positron emission tomography (FDG). Though these modal...

    Authors: Kenji Fukushima, Michinobu Nagao, Atsushi Yamamoto, Naoki Serizawa, Umiko Ishizaki, Atsushi Suzuki, Akiko Sakai, Eri Watanabe, Mitsuru Momose, Ichiei Kuji and Koichiro Abe
    Citation: European Journal of Hybrid Imaging 2019 3:9
    Content type: Original article Published on:

  12. Magnetic resonance imaging (MRI) and 2-[18F]-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography paired with computed tomography (PET/CT) are two commonly used imaging modalities in the complicated dia...

    Authors: Dennis Jan Willem Hulsen, Jan Geurts, Jacobus J. Arts, Daan Loeffen, Cristina Mitea and Stefan Adrian Vöö
    Citation: European Journal of Hybrid Imaging 2019 3:7
    Content type: Original article Published on:

  13. Routinely, there is a visual basis to nuclear medicine reporting: a reporter subjectively places a patient’s condition into one of multiple discrete classes based on what they see. The addition of a quantitati...

    Authors: James C. Ross, Dijana Vilić, Tom Sanderson, Stefan Vöö and John Dickson
    Citation: European Journal of Hybrid Imaging 2019 3:8
    Content type: Review Published on:

  15. People living with human immunodeficiency virus (HIV) infection have twice the risk of atherosclerotic vascular disease compared with non-infected individuals. Inflammation plays a critical role in the develop...

    Authors: Ismaheel O. Lawal, Alfred O. Ankrah, Anton C. Stoltz and Mike M. Sathekge
    Citation: European Journal of Hybrid Imaging 2019 3:5
    Content type: Review Published on:

  16. Detecting culprit coronary arteries in patients with ischemia using only myocardial perfusion single-photon emission computed tomography (SPECT) can be challenging. This study aimed to improve the detection of...

    Authors: Hiroto Yoneyama, Kenichi Nakajima, Junichi Taki, Hiroshi Wakabayashi, Shinro Matsuo, Takahiro Konishi, Koichi Okuda, Takayuki Shibutani, Masahisa Onoguchi and Seigo Kinuya
    Citation: European Journal of Hybrid Imaging 2019 3:4
    Content type: Original article Published on:

  17. Traditionally, isotope nephrography is considered as the method of choice to assess kidney function parameters in nuclear medicine. We propose a novel approach to determine the split function (SF), mean transi...

    Authors: Barbara K. Geist, Pascal Baltzer, Barbara Fueger, Martina Hamboeck, Thomas Nakuz, Laszlo Papp, Sazan Rasul, Lalith Kumar Shiyam Sundar, Marcus Hacker and Anton Staudenherz
    Citation: European Journal of Hybrid Imaging 2019 3:3
    Content type: Original article Published on:

  18. It is now about 8 years since the first whole-body integrated PET/MRI has been installed. First, reports on technical characteristics and system performance were published. Early after, reports on the first us...

    Authors: C. Rischpler, S. G. Nekolla, G. Heusch, L. Umutlu, T. Rassaf, P. Heusch, K. Herrmann and F. Nensa
    Citation: European Journal of Hybrid Imaging 2019 3:2
    Content type: Review Published on:

  20. The aim of this study was to evaluate primary tumor heterogeneity in patients with FDG-avid non-small cell lung cancer on PET/CT, with a view to optimising prognostic information from the metabolic signature o...

    Authors: N. M. Hughes, T. Mou, K. N. O’Regan, P. Murphy, J. N. O’Sullivan, E. Wolsztynski, J. Huang, M. P. Kennedy, J. F. Eary and F. O’Sullivan
    Citation: European Journal of Hybrid Imaging 2018 2:25
    Content type: Original article Published on:

  21. The combination of both functional and morphological information using three-phase bone scintigraphy and tomographic imaging with single photon emission tomography/computed tomography (SPECT/CT) allows precise...

    Authors: Willm Uwe Kampen, Lidija Antunovic, Andreas M. Luebke, Guido Sauter, Klaus Strobel and Frederic Paycha
    Citation: European Journal of Hybrid Imaging 2018 2:29
    Content type: Case report Published on:

  22. To explore quantitative metabolic and microstructural primary tumour parameters at pretreatment FDG-PET/CT and diffusion-weighted-magnetic resonance imaging (DW-MRI) in relation to clinical FIGO stage and outc...

    Authors: Vikram Rao Bollineni, Sigmund Ytre-Hauge, Ankush Gulati, Mari K. Halle, Kathrine Woie, Øyvind Salvesen, Jone Trovik, Camilla Krakstad and Ingfrid S. Haldorsen
    Citation: European Journal of Hybrid Imaging 2018 2:24
    Content type: Original article Published on:

  23. Both constrast-enhanced computed tomography (ceCT) and 18F-Fluorodeoxyglucose positron emission tomography (PET) are widely used for evaluation of colorectal cancer. Not infrequently patients undergo both tests, ...

    Authors: Kenneth S. K. Yap, Ojas H. Mehta, Wing Fai Eddie Lau, Tim Akhurst, Satish Warrier, Alexander Heriot and Rodney J. Hicks
    Citation: European Journal of Hybrid Imaging 2018 2:28
    Content type: Original article Published on:

  24. A 59 year old patient was referred to our department to detect disease activity related to clinical symptoms of tiredness, weight loss and an elevated serum serotonine, suspicious of a neuro-endocrine tumour. ...

    Authors: Gilles N. Stormezand, Andor W. J. M. Glaudemans, Riemer H. J. A. Slart and Rudi A. J. O. Dierckx
    Citation: European Journal of Hybrid Imaging 2018 2:23
    Content type: Case report Published on:

  25. Idiopathic Pulmonary Fibrosis (IPF) is a progressive and irreversible disease leading to terminal respiratory insufficiency. Fluorodeoxyglucose ([18F]-FDG) PET/CT has been proposed to track the activity of the...

    Authors: A. Castiaux, G. Van Simaeys, S. Goldman and B. Bondue
    Citation: European Journal of Hybrid Imaging 2018 2:27
    Content type: Original article Published on:

  26. Single photon emission tomography/computed tomography (SPECT/CT) combines the strengths of bone scintigraphy and CT and serve as an important alternative to magnetic resonance (MR) imaging in carpal trauma patien...

    Authors: Klaus Strobel, Lidija Antunovic, Wouter van der Bruggen, Gopinath Gnanasegaran, Willm Uwe Kampen, Tim Van den Wyngaert, Edmond Rust, Torsten Kuwert and Frédéric Paycha
    Citation: European Journal of Hybrid Imaging 2018 2:21
    Content type: Case report Published on:

  27. Correct primary staging is mandatory for therapy selection and to determine prognosis in prostate cancer patients. Commonly used diagnostic procedures including Computed Tomography (CT), Magnetic Resonance Ima...

    Authors: Maurits Wondergem, Friso M van der Zant, Ton A Roeleveld, Sandra Srbljin, Marina S Kartachova, Annemarie van Dongen, Vera Franken and Remco J J Knol
    Citation: European Journal of Hybrid Imaging 2018 2:26
    Content type: Original article Published on:

  28. Breast cancer heterogeneity reflects the complex biology of this disease. Breast cancer subtypes, as identified either by immunohistochemistry (IHC) or by gene expression analysis, present different molecular ...

    Authors: Ioannis Iakovou, Evanthia Giannoula, Areti Gkantaifi, Sofia Levva and Savvas Frangos
    Citation: European Journal of Hybrid Imaging 2018 2:20
    Content type: Review Published on:

  29. To determine and compare the diagnostic accuracy of fluoride-PET/CT (NaF-PET/CT), choline-PET/CT, whole-body bone SPECT/CT (WB-SPECT/CT) and whole-body MRI (WB-MRI) for the detection of bone metastases in pati...

    Authors: Eva Dyrberg, Helle W. Hendel, Vibeke B. Løgager, Claus Madsen, Erik M. Pedersen, Bo Zerahn and Henrik S. Thomsen
    Citation: European Journal of Hybrid Imaging 2018 2:19
    Content type: Original article Published on:

  30. 131I radioactive iodine therapy (RAI) has been commonly applied for metastatic differentiated thyroid cancer (DTC) and played an adjunctive role to total thyroidectomy. However, there is no reliable method to pre...

    Authors: Xieyi Zhang, Tetsuya Higuchi, Arifudin Achmad, Anu Bhattarai, Hiroyasu Tomonaga, Huong Nguyen Thu, Aiko Yamaguchi, Hiromi Hirasawa, Ayako Taketomi-Takahashi and Yoshito Tsushima
    Citation: European Journal of Hybrid Imaging 2018 2:22
    Content type: Original article Published on:

  31. In pulmonary malignancies pre-interventional 3D estimation of relative lobar perfusion is established to predict post-interventional functional outcome particularly in patients with borderline lung function. A...

    Authors: Daniela Knollmann, Jerome Avondo and Wolfgang M. Schaefer
    Citation: European Journal of Hybrid Imaging 2018 2:18
    Content type: Original article Published on:

  32. 99mTechnetium-HDP (HDP) bone scans differentiate transthyretin (ATTR) cardiac amyloid from other infiltrative myocardial diseases. These scans are not quantitative and are assessed by comparing myocardial upta...

    Authors: Stuart C. Ramsay, Karen Lindsay, William Fong, Shaun Patford, John Younger and John Atherton
    Citation: European Journal of Hybrid Imaging 2018 2:17
    Content type: Original article Published on:

  33. The aim of this study was to determine whether lymph node metastasis on pre-treatment 18F-choline PET/CT is an independent prognostic factor for biochemical recurrence (BCR), skeletal metastasis, and cancer speci...

    Authors: Henrik Kjölhede, Helén Almquist, Kerstin Lyttkens and Ola Bratt
    Citation: European Journal of Hybrid Imaging 2018 2:16
    Content type: Original article Published on:

  34. Machine learning (ML) represents a family of algorithms that has rapidly developed within the last years in a wide variety of knowledge areas. ML is able to elucidate and grasp complex patterns from data in or...

    Authors: Luis Eduardo Juarez-Orozco, Octavio Martinez-Manzanera, Sergey V. Nesterov, Sami Kajander and Juhani Knuuti
    Citation: European Journal of Hybrid Imaging 2018 2:15
    Content type: Review Published on:

  35. Ewing sarcoma (ES) is currently staged using Radiography, ultrasound, computed tomography (CT), magnetic resonance imaging (MRI) and skeletal scintigraphy (bone scan). 18F- fluorodeoxyglucose Positron Emission To...

    Authors: Boel Johnsen, Kristine Eldevik Fasmer, Kjetil Boye, Karen Rosendahl, Clement Trovik, Martin Biermann and Stein Magnus Aukland
    Citation: European Journal of Hybrid Imaging 2018 2:13
    Content type: Original article Published on:

  36. With primitive approaches, the diagnosis and therapy were operated at the cellular, molecular, or even at the genetic level. As the diagnostic techniques are more concentrated towards molecular level, multi mo...

    Authors: Sikkandhar Musafargani, Krishna Kanta Ghosh, Sachin Mishra, Pachaiyappan Mahalakshmi, Parasuraman Padmanabhan and Balázs Gulyás
    Citation: European Journal of Hybrid Imaging 2018 2:12
    Content type: Review Published on:

  37. Cardiac imaging by means of myocardial Positron Emission Tomography/Computed Tomography (PET/CT) is being used increasingly to assess coronary artery disease, to guide revascularization decisions with more acc...

    Authors: Opstal TSJ, Knol RJJ, Cornel JH, Wondergem M and van der Zant FM
    Citation: European Journal of Hybrid Imaging 2018 2:11
    Content type: Original article Published on:

  38. Dopamine transporter (DaT) 123I–FP-CIT scans most commonly are interpreted visually. Alternatively, absolute quantitation of radiopharmaceutical uptake may improve scan accuracy. However, neither approach accomod...

    Authors: Kenneth J. Nichols, Brandon Chen, Maria B. Tomas and Christopher J. Palestro
    Citation: European Journal of Hybrid Imaging 2018 2:10
    Content type: Original article Published on:

  39. The aim of this study was to prospectively compare the detection rate of 68Ga-PSMA versus 11C-Choline in men with prostate cancer with biochemical recurrence and to demonstrate the added value of a tri-modality P...

    Authors: Omar Alonso, Gerardo dos Santos, Margarita García Fontes, Henia Balter and Henry Engler
    Citation: European Journal of Hybrid Imaging 2018 2:9
    Content type: Original article Published on:

  40. Positron emission tomography (PET) and magnetic resonance imaging (MRI) have both been used for decades in cardiovascular imaging. Since 2010, hybrid PET/MRI using sequential and integrated scanner platforms h...

    Authors: Felix Nensa, Fabian Bamberg, Christoph Rischpler, Leon Menezes, Thorsten D. Poeppel, Christian la Fougère, Dietrich Beitzke, Sazan Rasul, Christian Loewe, Konstantin Nikolaou, Jan Bucerius, Andreas Kjaer, Matthias Gutberlet, Niek H. Prakken, Rozemarijn Vliegenthart, Riemer H. J. A. Slart…
    Citation: European Journal of Hybrid Imaging 2018 2:14
    Content type: Guideline Published on:

  41. A vast spectrum of lower limb bone and joint disorders (hip, knee, ankle, foot) present with a common clinical presentation: limping. Too often this symptom generates an inefficient cascade of imaging studies.

    Authors: H. K. Mohan, K. Strobel, W. van der Bruggen, G. Gnanasegaran, W. U. Kampen, T. Kuwert, T. Van den Wyngaert and F. Paycha
    Citation: European Journal of Hybrid Imaging 2018 2:8
    Content type: Review Published on:

  42. Unilateral condylar hyperplasia (UCH) of the mandible, or Hypercondylia, is a pathological condition that determines an abnormal growth of the affected condyle.

    Authors: G. M. Lima, S. Diodato, E. Costabile, G. Cicoria, S. Civollani, C. Marchetti, P. L. Guidalotti, C. Pettinato, C. Nanni and S. Fanti
    Citation: European Journal of Hybrid Imaging 2018 2:7
    Content type: Original article Published on:

  44. The diagnostic performance of SPECT-only imaging for takotsubo cardiomyopathy (TC) is limited due to the lack of coronary artery distribution information. The aim of this study was to evaluate the diagnostic p...

    Authors: Yasuro Sugihara, Yoshimitsu Fukushima, Shin-ichiro Kumita, Hitoshi Takano and Wataru Shimizu
    Citation: European Journal of Hybrid Imaging 2018 2:5
    Content type: Original article Published on:

  45. to determine the clinical significance of ground glass pulmonary nodules, either pure (GGNs) or mixed with the presence of solid component (MPNs), in patients with known pulmonary or extra-thoracic malignancie...

    Authors: Laura Evangelista, Annalori Panunzio, Elena Scagliori and Paolo Sartori
    Citation: European Journal of Hybrid Imaging 2018 2:2
    Content type: Original article Published on:

  47. 18F–FDG PET/CT has been proposed in the evaluation of the disease activity in rheumatoid arthritis (RA). The goals of this study were to evaluate the reproducibility of the technique, to compare metabolic parame....

    Authors: Pacôme FOSSE, Marie-Joelle KAISER, Gauthier NAMUR, Dominique de Seny, Michel G. MALAISE and Roland HUSTINX
    Citation: European Journal of Hybrid Imaging 2018 2:6
    Content type: Original article Published on:

  48. Hybrid imaging plays a central role in the diagnosis and management of a wide range of malignancies at all stages. In this article, we review the most pertinent historical developments, emerging clinical appli...

    Authors: Andreas G. Wibmer, Hedvig Hricak, Gary A. Ulaner and Wolfgang Weber
    Citation: European Journal of Hybrid Imaging 2018 2:1
    Content type: Review Published on:

  49. Several diagnostic imaging methodologies are available for the clinical evaluation of sarcoidosis, but all have their limitations. FDG PET/CT is frequently used, but this technique does not provide optimal res...

    Authors: Riemer H. J. A. Slart, Klaas-Pieter Koopmans, Peter Paul van Geel, Henk Kramer, Harry J. M. Groen, C. Tji-Joong Gan, Niek H. J. Prakken, Andor W. J. M. Glaudemans and George D. Nossent
    Citation: European Journal of Hybrid Imaging 2017 1:7
    Content type: Short communication Published on:

  50. TNM Stage 3B encompasses a wide range of primary tumor and nodal metastatic tumor burden. This study aimed to evaluate the prognostic value of quantitative FDG PET/CT parameters in patients with newly diagnose...

    Authors: Brittany Z. Dashevsky, Chenpeng Zhang, Li Yan, Cindy Yuan, Lingyun Xiong, Yongmei Liu, Haiyan Liu, Feng-Ming Spring Kong and Yonglin Pu
    Citation: European Journal of Hybrid Imaging 2017 1:8
    Content type: Original article Published on:
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