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  1. A 59 year old patient was referred to our department to detect disease activity related to clinical symptoms of tiredness, weight loss and an elevated serum serotonine, suspicious of a neuro-endocrine tumour. ...

    Authors: Gilles N. Stormezand, Andor W. J. M. Glaudemans, Riemer H. J. A. Slart and Rudi A. J. O. Dierckx
    Citation: European Journal of Hybrid Imaging 2018 2:23
    Content type: Case report Published on:

  2. Idiopathic Pulmonary Fibrosis (IPF) is a progressive and irreversible disease leading to terminal respiratory insufficiency. Fluorodeoxyglucose ([18F]-FDG) PET/CT has been proposed to track the activity of the...

    Authors: A. Castiaux, G. Van Simaeys, S. Goldman and B. Bondue
    Citation: European Journal of Hybrid Imaging 2018 2:27
    Content type: Original article Published on:

  3. Single photon emission tomography/computed tomography (SPECT/CT) combines the strengths of bone scintigraphy and CT and serve as an important alternative to magnetic resonance (MR) imaging in carpal trauma patien...

    Authors: Klaus Strobel, Lidija Antunovic, Wouter van der Bruggen, Gopinath Gnanasegaran, Willm Uwe Kampen, Tim Van den Wyngaert, Edmond Rust, Torsten Kuwert and Frédéric Paycha
    Citation: European Journal of Hybrid Imaging 2018 2:21
    Content type: Case report Published on:

  4. Correct primary staging is mandatory for therapy selection and to determine prognosis in prostate cancer patients. Commonly used diagnostic procedures including Computed Tomography (CT), Magnetic Resonance Ima...

    Authors: Maurits Wondergem, Friso M van der Zant, Ton A Roeleveld, Sandra Srbljin, Marina S Kartachova, Annemarie van Dongen, Vera Franken and Remco J J Knol
    Citation: European Journal of Hybrid Imaging 2018 2:26
    Content type: Original article Published on:

  5. Breast cancer heterogeneity reflects the complex biology of this disease. Breast cancer subtypes, as identified either by immunohistochemistry (IHC) or by gene expression analysis, present different molecular ...

    Authors: Ioannis Iakovou, Evanthia Giannoula, Areti Gkantaifi, Sofia Levva and Savvas Frangos
    Citation: European Journal of Hybrid Imaging 2018 2:20
    Content type: Review Published on:

  6. To determine and compare the diagnostic accuracy of fluoride-PET/CT (NaF-PET/CT), choline-PET/CT, whole-body bone SPECT/CT (WB-SPECT/CT) and whole-body MRI (WB-MRI) for the detection of bone metastases in pati...

    Authors: Eva Dyrberg, Helle W. Hendel, Vibeke B. Løgager, Claus Madsen, Erik M. Pedersen, Bo Zerahn and Henrik S. Thomsen
    Citation: European Journal of Hybrid Imaging 2018 2:19
    Content type: Original article Published on:

  7. 131I radioactive iodine therapy (RAI) has been commonly applied for metastatic differentiated thyroid cancer (DTC) and played an adjunctive role to total thyroidectomy. However, there is no reliable method to pre...

    Authors: Xieyi Zhang, Tetsuya Higuchi, Arifudin Achmad, Anu Bhattarai, Hiroyasu Tomonaga, Huong Nguyen Thu, Aiko Yamaguchi, Hiromi Hirasawa, Ayako Taketomi-Takahashi and Yoshito Tsushima
    Citation: European Journal of Hybrid Imaging 2018 2:22
    Content type: Original article Published on:

  8. In pulmonary malignancies pre-interventional 3D estimation of relative lobar perfusion is established to predict post-interventional functional outcome particularly in patients with borderline lung function. A...

    Authors: Daniela Knollmann, Jerome Avondo and Wolfgang M. Schaefer
    Citation: European Journal of Hybrid Imaging 2018 2:18
    Content type: Original article Published on:

  9. 99mTechnetium-HDP (HDP) bone scans differentiate transthyretin (ATTR) cardiac amyloid from other infiltrative myocardial diseases. These scans are not quantitative and are assessed by comparing myocardial upta...

    Authors: Stuart C. Ramsay, Karen Lindsay, William Fong, Shaun Patford, John Younger and John Atherton
    Citation: European Journal of Hybrid Imaging 2018 2:17
    Content type: Original article Published on:

  10. The aim of this study was to determine whether lymph node metastasis on pre-treatment 18F-choline PET/CT is an independent prognostic factor for biochemical recurrence (BCR), skeletal metastasis, and cancer speci...

    Authors: Henrik Kjölhede, Helén Almquist, Kerstin Lyttkens and Ola Bratt
    Citation: European Journal of Hybrid Imaging 2018 2:16
    Content type: Original article Published on:

  11. Machine learning (ML) represents a family of algorithms that has rapidly developed within the last years in a wide variety of knowledge areas. ML is able to elucidate and grasp complex patterns from data in or...

    Authors: Luis Eduardo Juarez-Orozco, Octavio Martinez-Manzanera, Sergey V. Nesterov, Sami Kajander and Juhani Knuuti
    Citation: European Journal of Hybrid Imaging 2018 2:15
    Content type: Review Published on:

  12. Ewing sarcoma (ES) is currently staged using Radiography, ultrasound, computed tomography (CT), magnetic resonance imaging (MRI) and skeletal scintigraphy (bone scan). 18F- fluorodeoxyglucose Positron Emission To...

    Authors: Boel Johnsen, Kristine Eldevik Fasmer, Kjetil Boye, Karen Rosendahl, Clement Trovik, Martin Biermann and Stein Magnus Aukland
    Citation: European Journal of Hybrid Imaging 2018 2:13
    Content type: Original article Published on:

  13. With primitive approaches, the diagnosis and therapy were operated at the cellular, molecular, or even at the genetic level. As the diagnostic techniques are more concentrated towards molecular level, multi mo...

    Authors: Sikkandhar Musafargani, Krishna Kanta Ghosh, Sachin Mishra, Pachaiyappan Mahalakshmi, Parasuraman Padmanabhan and Balázs Gulyás
    Citation: European Journal of Hybrid Imaging 2018 2:12
    Content type: Review Published on:

  14. Cardiac imaging by means of myocardial Positron Emission Tomography/Computed Tomography (PET/CT) is being used increasingly to assess coronary artery disease, to guide revascularization decisions with more acc...

    Authors: Opstal TSJ, Knol RJJ, Cornel JH, Wondergem M and van der Zant FM
    Citation: European Journal of Hybrid Imaging 2018 2:11
    Content type: Original article Published on:

  15. Dopamine transporter (DaT) 123I–FP-CIT scans most commonly are interpreted visually. Alternatively, absolute quantitation of radiopharmaceutical uptake may improve scan accuracy. However, neither approach accomod...

    Authors: Kenneth J. Nichols, Brandon Chen, Maria B. Tomas and Christopher J. Palestro
    Citation: European Journal of Hybrid Imaging 2018 2:10
    Content type: Original article Published on:

  16. The aim of this study was to prospectively compare the detection rate of 68Ga-PSMA versus 11C-Choline in men with prostate cancer with biochemical recurrence and to demonstrate the added value of a tri-modality P...

    Authors: Omar Alonso, Gerardo dos Santos, Margarita García Fontes, Henia Balter and Henry Engler
    Citation: European Journal of Hybrid Imaging 2018 2:9
    Content type: Original article Published on:

  17. Positron emission tomography (PET) and magnetic resonance imaging (MRI) have both been used for decades in cardiovascular imaging. Since 2010, hybrid PET/MRI using sequential and integrated scanner platforms h...

    Authors: Felix Nensa, Fabian Bamberg, Christoph Rischpler, Leon Menezes, Thorsten D. Poeppel, Christian la Fougère, Dietrich Beitzke, Sazan Rasul, Christian Loewe, Konstantin Nikolaou, Jan Bucerius, Andreas Kjaer, Matthias Gutberlet, Niek H. Prakken, Rozemarijn Vliegenthart, Riemer H. J. A. Slart…
    Citation: European Journal of Hybrid Imaging 2018 2:14
    Content type: Guideline Published on:

  18. A vast spectrum of lower limb bone and joint disorders (hip, knee, ankle, foot) present with a common clinical presentation: limping. Too often this symptom generates an inefficient cascade of imaging studies.

    Authors: H. K. Mohan, K. Strobel, W. van der Bruggen, G. Gnanasegaran, W. U. Kampen, T. Kuwert, T. Van den Wyngaert and F. Paycha
    Citation: European Journal of Hybrid Imaging 2018 2:8
    Content type: Review Published on:

  19. Unilateral condylar hyperplasia (UCH) of the mandible, or Hypercondylia, is a pathological condition that determines an abnormal growth of the affected condyle.

    Authors: G. M. Lima, S. Diodato, E. Costabile, G. Cicoria, S. Civollani, C. Marchetti, P. L. Guidalotti, C. Pettinato, C. Nanni and S. Fanti
    Citation: European Journal of Hybrid Imaging 2018 2:7
    Content type: Original article Published on:

  21. The diagnostic performance of SPECT-only imaging for takotsubo cardiomyopathy (TC) is limited due to the lack of coronary artery distribution information. The aim of this study was to evaluate the diagnostic p...

    Authors: Yasuro Sugihara, Yoshimitsu Fukushima, Shin-ichiro Kumita, Hitoshi Takano and Wataru Shimizu
    Citation: European Journal of Hybrid Imaging 2018 2:5
    Content type: Original article Published on:

  22. to determine the clinical significance of ground glass pulmonary nodules, either pure (GGNs) or mixed with the presence of solid component (MPNs), in patients with known pulmonary or extra-thoracic malignancie...

    Authors: Laura Evangelista, Annalori Panunzio, Elena Scagliori and Paolo Sartori
    Citation: European Journal of Hybrid Imaging 2018 2:2
    Content type: Original article Published on:

  24. 18F–FDG PET/CT has been proposed in the evaluation of the disease activity in rheumatoid arthritis (RA). The goals of this study were to evaluate the reproducibility of the technique, to compare metabolic parame....

    Authors: Pacôme FOSSE, Marie-Joelle KAISER, Gauthier NAMUR, Dominique de Seny, Michel G. MALAISE and Roland HUSTINX
    Citation: European Journal of Hybrid Imaging 2018 2:6
    Content type: Original article Published on:

  25. Hybrid imaging plays a central role in the diagnosis and management of a wide range of malignancies at all stages. In this article, we review the most pertinent historical developments, emerging clinical appli...

    Authors: Andreas G. Wibmer, Hedvig Hricak, Gary A. Ulaner and Wolfgang Weber
    Citation: European Journal of Hybrid Imaging 2018 2:1
    Content type: Review Published on:

  26. Several diagnostic imaging methodologies are available for the clinical evaluation of sarcoidosis, but all have their limitations. FDG PET/CT is frequently used, but this technique does not provide optimal res...

    Authors: Riemer H. J. A. Slart, Klaas-Pieter Koopmans, Peter Paul van Geel, Henk Kramer, Harry J. M. Groen, C. Tji-Joong Gan, Niek H. J. Prakken, Andor W. J. M. Glaudemans and George D. Nossent
    Citation: European Journal of Hybrid Imaging 2017 1:7
    Content type: Short communication Published on:

  27. The purpose of the study to evaluate possibilities of CT-perfusion and PET methods with 18F–FDG and 18F–fluorocholine in the complex diagnosis of hepatocellular carcinoma. The study included the results of PET...

    Authors: P. E. Tulin, M. B. Dolgushin, A. A. Odzharova, A. I. Mikhaylov, B. M. Medvedeva, S. V. Shiryaev and B. I. Dolgushin
    Citation: European Journal of Hybrid Imaging 2017 1:13
    Content type: Original article Published on:

  28. TNM Stage 3B encompasses a wide range of primary tumor and nodal metastatic tumor burden. This study aimed to evaluate the prognostic value of quantitative FDG PET/CT parameters in patients with newly diagnose...

    Authors: Brittany Z. Dashevsky, Chenpeng Zhang, Li Yan, Cindy Yuan, Lingyun Xiong, Yongmei Liu, Haiyan Liu, Feng-Ming Spring Kong and Yonglin Pu
    Citation: European Journal of Hybrid Imaging 2017 1:8
    Content type: Original article Published on:

  29. The clinical utility of 18F–choline positron emission tomography fused with computed tomography (PET/CT) in all men with high-risk prostate cancer is still uncertain, because of selection of patients in previous ...

    Authors: Henrik Kjölhede, Helen Almquist, Kerstin Lyttkens and Ola Bratt
    Citation: European Journal of Hybrid Imaging 2017 1:12
    Content type: Original article Published on:

  30. Positron emission tomography/magnetic resonance imaging (PET/MR) is a new multimodal imaging technique, which might improve the diagnostic performance not only in oncological patients but also in patients with...

    Authors: Isabel Rauscher, Matthias Eiber, Hana Algül, Jens T. Siveke, Gregor Weirich, Anna M. Schlitter and Ambros J. Beer
    Citation: European Journal of Hybrid Imaging 2017 1:11
    Content type: Case Report Published on:

  31. Only about 1% of all head and neck lateral or paramedian cancers described in the scientific literature shows, in staging, contralateral cervical adenopathy without ipsilateral pathological involvement of lymp...

    Authors: G. M. Lima, A. Matti, L. Burgio, C. Nanni, P. Castellucci and S. Fanti
    Citation: European Journal of Hybrid Imaging 2017 1:1
    Content type: Case report Published on:

  32. Attenuation correction is one of the most important steps in producing quantitative PET image data. In hybrid PET-MRI systems, this correction is far from trivial, as MRI data are not correlated to PET attenua...

    Authors: Florian Büther, Benjamin Noto, Katharina Auf der Springe, Thomas Allkemper and Lars Stegger
    Citation: European Journal of Hybrid Imaging 2017 1:10
    Content type: Case Report Published on:

  33. We evaluated the feasibility and accuracy of 11C–choline PET-CT/TRUS fusion-guided prostate biopsy in men with persistently elevated PSA and negative mpMRI or contraindication to MRI, after previous negative b...

    Authors: Massimo Lazzeri, Egesta Lopci, Giovanni Lughezzani, Piergiuseppe Colombo, Paolo Casale, Rodolfo Hurle, Alberto Saita, Lorenzo Leonardi, Giuliana Lista, Roberto Peschechera, Luisa Pasini, Marcello Rodari, Silvia Zandegiacomo, Alessio Benetti, Pasquale Cardone, Federica Mrakic…
    Citation: European Journal of Hybrid Imaging 2017 1:9
    Content type: Original article Published on:

  35. 11C–choline PET/CT is a widely-used tool for the diagnostic of prostate cancer (PCa). In literature, a great variability of local relapse (LR) detection rate is reported. The aim of this study is to provide po...

    Authors: A. Matti, G. M. Lima, L. Zanoni, C. Pultrone, R. Schiavina, F. Lodi, S. Fanti and C. Nanni
    Citation: European Journal of Hybrid Imaging 2017 1:5
    Content type: Short communication Published on:

  36. PET-MR scanners are beginning to be employed for quantitative myocardial perfusion imaging. In order to examine simultaneous perfusion calculations, this work describes a feasibility study of simultaneous PET-...

    Authors: Jim O’Doherty, Eva Sammut, Paul Schleyer, James Stirling, Muhummad Sohaib Nazir, Paul K. Marsden and Amedeo Chiribiri
    Citation: European Journal of Hybrid Imaging 2017 1:4
    Content type: Original article Published on:

  37. significance of incidental thyroid 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) uptake on positron emission tomography/computed tomography (PET/CT) scans remains controversial. We aimed to evaluate the ability of [

    Authors: M. Sollini, L. Cozzi, G. Pepe, L. Antunovic, A. Lania, L. Di Tommaso, P. Magnoni, P. A. Erba and M. Kirienko
    Citation: European Journal of Hybrid Imaging 2017 1:3
    Content type: Original article Published on:

  38. To investigate the improvement of prognostication of active bone metastatic burden by discriminating bone metastases from degenerative changes in hot foci, using skeletal standardized uptake values (SUVs) by q...

    Authors: Ichiei Kuji, Tomohiko Yamane, Akira Seto, Yota Yasumizu, Suguru Shirotake and Masafumi Oyama
    Citation: European Journal of Hybrid Imaging 2017 1:2
    Content type: Original article Published on:
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